SCHEMBL16601823

SCHEMBL16601823

CCc1cccc(C)c1N1C(=O)c2ccc3c4c(-c5ccccc5)cc5c6c(ccc(c7c(-c8ccccc8)cc(c2c37)C1=O)c64)C(=O)N(C(CC)CO)C5=O

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 4/20 0.38
DPP4 P27487 4/20 0.38
PDCD1 Q15116 9/20 0.33
CD274 Q9NZQ7 9/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
ALDH1A1 P00352 2/20 0.32
MAPT P10636 2/20 0.32
HSD17B10 Q99714 2/20 0.32
USP2 O75604 1/20 0.32
GAA P10253 1/20 0.32
CRHBP P24387 1/20 0.32
CASP1 P29466 1/20 0.32
BRCA1 P38398 1/20 0.32
CASP7 P55210 1/20 0.32
HBB P68871 1/20 0.32
CRHR2 Q13324 1/20 0.32
TYMS P04818 1/20 0.31
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15764232 0.88 DPP4 (0.42) ANPEPDPP4MEN1KMT2AALDH1A1
SCHEMBL12629126 0.87 DPP4 (0.45) ANPEPDPP4MEN1KMT2AALDH1A1
SCHEMBL16602020 0.86 ANPEP (0.37) ANPEPDPP4
SCHEMBL16601825 0.83 DPP4 (0.43) ANPEPDPP4MEN1KMT2AALDH1A1
SCHEMBL16601644 0.83 DPP4 (0.47) ANPEPDPP4MEN1KMT2AALDH1A1
SCHEMBL16601805 0.82 DPP4 (0.40) ANPEPDPP4MEN1KMT2AALDH1A1
SCHEMBL16601831 0.81 ANPEP (0.48) ANPEPDPP4MEN1KMT2AALDH1A1
SCHEMBL25582868 0.81 TERT (0.34) MEN1KMT2AALDH1A1HSD17B10GAA
SCHEMBL12657845 0.81 ANPEP (0.52) ANPEPDPP4MEN1KMT2AALDH1A1
SCHEMBL15764203 0.80 ANPEP (0.46) ANPEPDPP4PDCD1CD274MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed