SCHEMBL16601825

SCHEMBL16601825

CCc1cccc(C)c1N1C(=O)c2ccc3c4ccc5c6c(ccc(c7ccc(c2c37)C1=O)c64)C(=O)N(C(CO)CO)C5=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 5/20 0.43
ANPEP P15144 4/20 0.43
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
CRHBP P24387 2/20 0.35
CRHR2 Q13324 2/20 0.35
ALDH1A1 P00352 2/20 0.35
USP2 O75604 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
CASP1 P29466 1/20 0.35
BRCA1 P38398 1/20 0.35
CASP7 P55210 1/20 0.35
HBB P68871 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TERT O14746 3/20 0.33
BRD1 O95696 2/20 0.33
TAF1 P21675 2/20 0.33
BRPF1 P55201 2/20 0.33
TAF1L Q8IZX4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15764232 0.96 DPP4 (0.42) DPP4ANPEPMEN1KMT2ACRHBP
SCHEMBL16601644 0.95 DPP4 (0.47) DPP4ANPEPMEN1KMT2ACRHBP
SCHEMBL12629126 0.91 DPP4 (0.45) DPP4ANPEPMEN1KMT2ACRHBP
SCHEMBL16656207 0.89 DPP4 (0.43) DPP4ANPEPMEN1KMT2ACRHBP
SCHEMBL16601831 0.88 ANPEP (0.48) DPP4ANPEPMEN1KMT2ACRHBP
SCHEMBL16601823 0.83 ANPEP (0.38) DPP4ANPEPMEN1KMT2ACRHBP
SCHEMBL16601631 0.83 DPP4 (0.46) DPP4ANPEPMEN1KMT2ACRHBP
SCHEMBL12657845 0.83 ANPEP (0.52) DPP4ANPEPMEN1KMT2ACRHBP
SCHEMBL15764235 0.83 DPP4 (0.37) DPP4ANPEPMEN1KMT2ACRHBP
SCHEMBL13045764 0.83 DPP4 (0.55) DPP4ANPEPMEN1KMT2ACRHBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed