SCHEMBL16601831

SCHEMBL16601831

CCc1cccc(CC)c1N1C(=O)c2ccc3c4ccc5c6c(ccc(c7ccc(c2c37)C1=O)c64)C(=O)N(C(CC)CO)C5=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 4/20 0.48
DPP4 P27487 4/20 0.48
CRHBP P24387 2/20 0.38
CRHR2 Q13324 2/20 0.38
TERT O14746 4/20 0.34
LMNA P02545 4/20 0.33
MAPT P10636 3/20 0.33
HTT P42858 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
STAT3 P40763 1/20 0.33
HIF1A Q16665 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
ALDH1A1 P00352 4/20 0.32
KDM4E B2RXH2 2/20 0.32
CYP1A2 P05177 1/20 0.32
POLB P06746 1/20 0.32
HPGD P15428 1/20 0.32
CYP2C19 P33261 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12657845 0.95 ANPEP (0.52) ANPEPDPP4CRHBPCRHR2LMNA
SCHEMBL15764232 0.93 DPP4 (0.42) ANPEPDPP4CRHBPCRHR2TERT
SCHEMBL16601825 0.88 DPP4 (0.43) ANPEPDPP4CRHBPCRHR2TERT
SCHEMBL12629126 0.88 DPP4 (0.45) ANPEPDPP4CRHBPCRHR2MAPT
SCHEMBL16601834 0.86 TERT (0.43) TERTLMNAHTTL3MBTL1STAT3
SCHEMBL8070665 0.84 ANPEP (0.59) ANPEPDPP4CRHBPCRHR2TERT
SCHEMBL16601824 0.84 TERT (0.35) ANPEPDPP4TERTSTAT3HIF1A
SCHEMBL16601644 0.83 DPP4 (0.47) ANPEPDPP4CRHBPCRHR2MAPT
SCHEMBL16601822 0.82 ANPEP (0.50) ANPEPDPP4CRHBPCRHR2L3MBTL1
SCHEMBL16601823 0.81 ANPEP (0.38) ANPEPDPP4CRHBPCRHR2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed