SCHEMBL16656207

SCHEMBL16656207

CCc1cccc(C)c1N1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(C(CO)CC(C)C)C3=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 6/20 0.43
ANPEP P15144 5/20 0.43
ALDH1A1 P00352 4/20 0.35
HSD17B10 Q99714 3/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
CRHBP P24387 2/20 0.34
CRHR2 Q13324 2/20 0.34
MAPT P10636 3/20 0.33
USP2 O75604 1/20 0.33
GAA P10253 1/20 0.33
CASP1 P29466 1/20 0.33
BRCA1 P38398 1/20 0.33
CASP7 P55210 1/20 0.33
HBB P68871 1/20 0.33
TP53 P04637 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HTT P42858 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16601644 0.93 DPP4 (0.47) DPP4ANPEPALDH1A1HSD17B10MEN1
SCHEMBL12629126 0.91 DPP4 (0.45) DPP4ANPEPALDH1A1HSD17B10MEN1
SCHEMBL16601825 0.89 DPP4 (0.43) DPP4ANPEPALDH1A1HSD17B10MEN1
SCHEMBL15764232 0.87 DPP4 (0.42) DPP4ANPEPALDH1A1HSD17B10MEN1
SCHEMBL12657845 0.83 ANPEP (0.52) DPP4ANPEPALDH1A1MEN1KMT2A
SCHEMBL13045764 0.83 DPP4 (0.55) DPP4ANPEPALDH1A1HSD17B10MEN1
SCHEMBL16601805 0.81 DPP4 (0.40) DPP4ANPEPALDH1A1HSD17B10MEN1
SCHEMBL15764213 0.80 ALDH1A1 (0.40) ALDH1A1MEN1KMT2AGAACASP1
SCHEMBL16602024 0.79 DPP4 (0.50) DPP4ANPEPALDH1A1HSD17B10MEN1
SCHEMBL16601823 0.79 ANPEP (0.38) DPP4ANPEPALDH1A1HSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed