Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.70 |
| ▸ | RAB9A | P51151 | 5/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | PTPRC | P08575 | 6/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | APAF1 | O14727 | 2/20 | 0.62 |
| ▸ | PTBP1 | P26599 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | GALK1 | P51570 | 2/20 | 0.62 |
| ▸ | BLM | P54132 | 2/20 | 0.62 |
| ▸ | SMAD3 | P84022 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31255810 | 0.90 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL31255811 | 0.90 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL28863139 | 0.87 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL17715429 | 0.87 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL57813 | 0.85 | NPC1 (0.80) | NPC1RAB9ASMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL30722379 | 0.85 | NPC1 (0.80) | NPC1RAB9ASMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL21993324 | 0.85 | NPC1 (0.80) | NPC1RAB9ASMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL1482692 | 0.83 | MEN1 (0.84) | NPC1RAB9ASMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL7322266 | 0.83 | MEN1 (0.84) | NPC1RAB9ASMN1; SMN2ALDH1A1CYP3A4 | |
| Anthraquinone SCHEMBL23363689 | 0.83 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012112-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-04-21 | — | — | US | disclosed |
| US-9012112-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-04-21 | — | — | US | disclosed |
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |