Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 6/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.46 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31734146 | 0.98 | KDM4E (0.53) | KDM4ESMN1; SMN2RAB9ANPC1ALOX5 | |
| SCHEMBL14141885 | 0.83 | ALOX5 (0.59) | KDM4ESMN1; SMN2RAB9ANPC1ALOX5 | |
| SCHEMBL5157521 | 0.80 | MEN1 (0.47) | KDM4ESMN1; SMN2CYP2C19CYP2C9CYP2D6 | |
| SCHEMBL14141735 | 0.80 | RAB9A (0.51) | KDM4ESMN1; SMN2RAB9ANPC1ALOX5 | |
| SCHEMBL12040235 | 0.80 | CYP3A4 (0.53) | KDM4ESMN1; SMN2RAB9ANPC1ALOX5 | |
| SCHEMBL290740 | 0.80 | CYP3A4 (0.62) | KDM4ESMN1; SMN2RAB9ANPC1ALOX5 | |
| SCHEMBL289945 | 0.80 | CYP3A4 (0.50) | KDM4ESMN1; SMN2RAB9ANPC1ALOX5 | |
| SCHEMBL289944 | 0.80 | CYP2A6 (0.53) | KDM4ESMN1; SMN2RAB9ANPC1ALOX5 | |
| SCHEMBL544650 | 0.79 | ALOX5 (0.55) | KDM4ESMN1; SMN2RAB9ANPC1ALOX5 | |
| SCHEMBL290282 | 0.77 | NPC1 (0.46) | KDM4ESMN1; SMN2RAB9ANPC1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108812681-B | Pesticidal compositions and methods related thereto | 美国陶氏益农公司 | 2021-02-26 | — | — | CN | disclosed |
| US-RE48057-E1 | Pesticidal compositions and related methods | DOW AGROSCIENCES LLC (US) | 2020-06-23 | — | — | US | disclosed |
| EP-3062619-B1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | DOW AGROSCIENCES LLC (US) | 2019-07-24 | — | — | EP | disclosed |
| EP-2614826-B1 | Process for preparation of thiazole derivatives | DOW AGROSCIENCES LLC (US) | 2017-03-01 | — | — | EP | disclosed |
| EP-2855468-B1 | PROCESSES TO PRODUCE CERTAIN 2-(PYRIDINE-3-YL)THIAZOLES | DOW AGROSCIENCES LLC (US) | 2016-11-02 | — | — | EP | disclosed |
| US-9445597-B2 | Pesticidal compositions and related methods | DOW AGROSCIENCES LLC (US) | 2016-09-20 | — | — | US | disclosed |
| EP-3062619-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | Dow AgroSciences LLC (US) | 2016-09-07 | — | — | EP | disclosed |
| WO-2015061151-A9 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | DOW AGROSCIENCES LLC (US) | 2016-04-21 | — | — | WO | disclosed |
| EP-2427191-B1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2016-03-16 | — | — | EP | disclosed |
| US-9137998-B2 | Pesticidal compositions and related methods | DOW AGROSCIENCES LLC (US) | 2015-09-22 | — | — | US | disclosed |
| WO-2015061151-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | DOW AGROSCIENCES LLC (US) | 2015-04-30 | — | — | WO | disclosed |
| US-20150111730-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | CORTEVA AGRISCIENCE LLC | 2015-04-23 | — | — | US | disclosed |
| US-20150111731-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | CORTEVA AGRISCIENCE LLC | 2015-04-23 | — | — | US | disclosed |
| US-8993769-B2 | Processes to produce certain 2-(pyridine-3-yl)thiazoles | DOW AGROSCIENCES, LLC. (US) | 2015-03-31 | — | — | US | disclosed |
| US-8993769-B2 | Processes to produce certain 2-(pyridine-3-yl)thiazoles | DOW AGROSCIENCES, LLC. (US) | 2015-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150111731-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | PTMS, CNP, ACHE | KDM4E 187/4885SMN1; SMN2 2389/4885RAB9A 1029/4885 |
| US-20150111730-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | ACHE, RDX, CHRM2 | KDM4E 1162/4885SMN1; SMN2 2418/4885RAB9A 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.