Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.35 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 2/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16601928 | 0.99 | ACHE (0.37) | ACHEPAOXGSTP1GSTM2LTA4H | |
| SCHEMBL16601934 | 0.99 | ACHE (0.37) | ACHEPAOXGSTP1GSTM2LTA4H | |
| SCHEMBL10099921 | 0.85 | ACHE (0.38) | ACHELTA4HFAAHDNM1HTR2C | |
| SCHEMBL17069546 | 0.83 | ACHE (0.31) | ACHEHTR2C | |
| SCHEMBL8739243 | 0.82 | ACHE (0.31) | ACHEKDM5AHTR2C | |
| SCHEMBL16140053 | 0.81 | ACHE (0.30) | ACHEPAOXHTR2C | |
| SCHEMBL25820448 | 0.76 | ACHE (0.35) | ACHEPAOXLTA4HFAAHDNM1 | |
| SCHEMBL12792529 | 0.76 | FAAH (0.48) | ACHEPAOXFAAHDNM1HTR2C | |
| SCHEMBL889254 | 0.76 | FAAH (0.48) | ACHEPAOXFAAHDNM1HTR2C | |
| SCHEMBL12792458 | 0.76 | FAAH (0.48) | ACHEPAOXFAAHDNM1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8992991-B2 | Multicomponent degradable cationic polymers | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-03-31 | — | — | US | disclosed |