Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17069546 | 0.96 | ACHE (0.31) | ACHEHTR2C | |
| SCHEMBL16140053 | 0.93 | ACHE (0.30) | ACHEHTR2C | |
| SCHEMBL10099921 | 0.93 | ACHE (0.38) | ACHEHTR2C | |
| SCHEMBL16601928 | 0.83 | ACHE (0.37) | ACHEHTR2CMEN1KMT2A | |
| SCHEMBL16601934 | 0.83 | ACHE (0.37) | ACHEHTR2CMEN1KMT2A | |
| SCHEMBL16601932 | 0.82 | ACHE (0.35) | ACHEHTR2CKDM5A | |
| SCHEMBL13071960 | 0.81 | KDM4E (0.42) | MEN1KMT2A | |
| SCHEMBL8738810 | 0.78 | HTR2C (0.51) | ACHEHTR2CMEN1KMT2A | |
| SCHEMBL25820448 | 0.78 | ACHE (0.35) | ACHE | |
| SCHEMBL16601935 | 0.78 | NAAA (0.45) | ACHEHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8992991-B2 | Multicomponent degradable cationic polymers | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-03-31 | — | — | US | disclosed |
| US-20120128782-A1 | Multicomponent Degradable Cationic Polymers | THE JOHNS HOPKINS UNIVERSITY (US) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120128782-A1 | Multicomponent Degradable Cationic Polymers | PEF1, FIBP, PARN | ACHE 4465/4885HTR2C 2124/4885MEN1 324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.