Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.58 |
| ▸ | NOS2 | P35228 | 1/20 | 0.58 |
| ▸ | ABL1 | P00519 | 1/20 | 0.56 |
| ▸ | BCR | P11274 | 1/20 | 0.56 |
| ▸ | CALM1 | P0DP23 | 7/20 | 0.56 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.50 |
| ▸ | TUBB | P07437 | 1/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18546194 | 0.91 | PTPN1 (0.71) | AKR1B1PTPN1NOS2ABL1BCR | |
| SCHEMBL16372690 | 0.89 | AKR1B1 (0.71) | AKR1B1PTPN1NOS2TNKS2ALOX5 | |
| SCHEMBL16601910 | 0.89 | PTPN1 (0.53) | AKR1B1PTPN1NOS2ABL1BCR | |
| SCHEMBL16372691 | 0.85 | TUBB4A (0.71) | AKR1B1PTPN1NOS2CALM1TNKS2 | |
| SCHEMBL17263518 | 0.83 | AKR1B1 (0.76) | AKR1B1PTPN1NOS2TNKS2ALOX5 | |
| SCHEMBL9491787 | 0.82 | CYP19A1 (0.68) | AKR1B1PTPN1NOS2CALM1CYP19A1 | |
| SCHEMBL1047550 | 0.80 | ABL1 (0.65) | ABL1BCRALOX5PTGS2 | |
| SCHEMBL16362239 | 0.80 | AKR1B1 (0.61) | AKR1B1PTPN1TNKS2ALOX5TUBB4A | |
| SCHEMBL15240817 | 0.79 | TNKS2 (0.67) | AKR1B1PTPN1TNKS2ALOX5TUBB4A | |
| SCHEMBL223826 | 0.79 | AKR1B1 (0.59) | AKR1B1TNKS2ALOX5GABRA1GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993689-B1 | Polyphenols and high-performance resins from syringaldehyde | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2015-03-31 | — | — | US | disclosed |