Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.71 |
| ▸ | NOS2 | P35228 | 1/20 | 0.71 |
| ▸ | CALM1 | P0DP23 | 7/20 | 0.67 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.63 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.63 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.63 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.63 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.63 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.54 |
| ▸ | PTGES | O14684 | 1/20 | 0.54 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16602200 | 0.91 | AKR1B1 (0.61) | PTPN1NOS2CALM1GABRA1GABRG2 | |
| SCHEMBL30451939 | 0.85 | CALM1 (0.81) | PTPN1NOS2CALM1GABRA1GABRG2 | |
| SCHEMBL16372690 | 0.84 | AKR1B1 (0.71) | PTPN1NOS2AKR1B1ALOX5TNKS2 | |
| Gigantol SCHEMBL29371870 | 0.83 | PTPN1 (1.00) | PTPN1NOS2CALM1GABRA1GABRG2 | |
| Gigantol SCHEMBL27845711 | 0.83 | PTPN1 (1.00) | PTPN1NOS2CALM1GABRA1GABRG2 | |
| SCHEMBL16601910 | 0.81 | PTPN1 (0.53) | PTPN1NOS2CALM1GABRA1GABRG2 | |
| SCHEMBL31388314 | 0.80 | PTPN1 (0.78) | PTPN1NOS2CALM1GABRA1GABRG2 | |
| SCHEMBL30940595 | 0.80 | PTPN1 (0.78) | PTPN1NOS2CALM1GABRA1GABRG2 | |
| SCHEMBL16125315 | 0.80 | PTPN1 (0.78) | PTPN1NOS2CALM1GABRA1GABRG2 | |
| SCHEMBL30940594 | 0.80 | PTPN1 (0.78) | PTPN1NOS2CALM1GABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109952286-B | Skin protection composition based on dendrobe components | 香港浸会大学 | 2022-03-22 | — | — | CN | disclosed |
| CN-110698328-A | Method for using dihydroresveratrol or stilbene derivatives and/or chemical variants thereof as antimicrobial agents | 香港浸会大学 | 2020-01-17 | — | — | CN | disclosed |
| US-10351500-B2 | Method of using of dihydro-resveratrol or its stilbenoid derivatives and/or chemical variants as antimicrobial agents | HONG KONG BAPTIST UNIVERSITY (HK) | 2019-07-16 | — | — | US | disclosed |
| US-10188590-B2 | Skin-protection composition containing Dendrobium-based ingredients | HONG KONG BAPTIST UNIVERSITY (HK) | 2019-01-29 | — | — | US | disclosed |
| US-10017442-B2 | Method of using dihydro-resveratrol or its stilbenoid derivatives and/or chemical variants in treatment of tumorous pathologies | HONG KONG BAPTIST UNIVERSITY (HK) | 2018-07-10 | — | — | US | disclosed |
| US-10017442-B2 | Method of using dihydro-resveratrol or its stilbenoid derivatives and/or chemical variants in treatment of tumorous pathologies | HONG KONG BAPTIST UNIVERSITY (HK) | 2018-07-10 | — | — | US | disclosed |
| US-10017442-B2 | Method of using dihydro-resveratrol or its stilbenoid derivatives and/or chemical variants in treatment of tumorous pathologies | HONG KONG BAPTIST UNIVERSITY (HK) | 2018-07-10 | — | — | US | disclosed |
| WO-2018090805-A1 | SKIN-PROTECTION COMPOSITION CONTAINING DENDROBIUM-BASED INGREDIENTS | HONG KONG BAPTIST UNIVERSITY (CN) | 2018-05-24 | — | — | WO | disclosed |
| US-20180118647-A1 | Method of Using dihydro-resveratrol or its stilbenoid derivatives and/or chemical variants in treatment of tumorous pathologies | HONG KONG BAPTIST UNIVERSITY (HK) | 2018-05-03 | — | — | US | disclosed |
| US-20180118647-A1 | Method of Using dihydro-resveratrol or its stilbenoid derivatives and/or chemical variants in treatment of tumorous pathologies | HONG KONG BAPTIST UNIVERSITY (HK) | 2018-05-03 | — | — | US | disclosed |
| US-20170290782-A1 | Method of Using dihydro-resveratrol or its stilbenoid derivatives and/or chemical variants in treatments of fibrotic and diabetic conditions | HONG KONG BAPTIST UNIVERSITY (HK) | 2017-10-12 | — | — | US | disclosed |
| US-20170290782-A1 | Method of Using dihydro-resveratrol or its stilbenoid derivatives and/or chemical variants in treatments of fibrotic and diabetic conditions | HONG KONG BAPTIST UNIVERSITY (HK) | 2017-10-12 | — | — | US | disclosed |
| US-20170290782-A1 | Method of Using dihydro-resveratrol or its stilbenoid derivatives and/or chemical variants in treatments of fibrotic and diabetic conditions | HONG KONG BAPTIST UNIVERSITY (HK) | 2017-10-12 | — | — | US | disclosed |
| US-9738581-B2 | Method of using dihydro-resveratrol or its stilbenoid derivatives and/or chemical variants in treatments of fibrotic and diabetic conditions | HONG KONG BAPTIST UNIVERSITY (HK) | 2017-08-22 | — | — | US | disclosed |
| US-9738581-B2 | Method of using dihydro-resveratrol or its stilbenoid derivatives and/or chemical variants in treatments of fibrotic and diabetic conditions | HONG KONG BAPTIST UNIVERSITY (HK) | 2017-08-22 | — | — | US | disclosed |
| US-20170057906-A1 | SKIN-PROTECTION COMPOSITION CONTAINING DENDROBIUM-BASED INGREDIENTS | HONG KONG BAPTIST UNIVERSITY | 2017-03-02 | — | — | US | disclosed |
| US-20170057906-A1 | SKIN-PROTECTION COMPOSITION CONTAINING DENDROBIUM-BASED INGREDIENTS | HONG KONG BAPTIST UNIVERSITY | 2017-03-02 | — | — | US | disclosed |
| US-20170057896-A1 | Method of Using dihydro-resveratrol or its stilbenoid derivatives and/or chemical variants in treatments of fibrotic and diabetic conditions | HONG KONG BAPTIST UNIVERSITY | 2017-03-02 | — | — | US | disclosed |
| US-20170057896-A1 | Method of Using dihydro-resveratrol or its stilbenoid derivatives and/or chemical variants in treatments of fibrotic and diabetic conditions | HONG KONG BAPTIST UNIVERSITY | 2017-03-02 | — | — | US | disclosed |
| US-20170057906-A1 | SKIN-PROTECTION COMPOSITION CONTAINING DENDROBIUM-BASED INGREDIENTS | HONG KONG BAPTIST UNIVERSITY | 2017-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170057906-A1 | SKIN-PROTECTION COMPOSITION CONTAINING DENDROBIUM-BASED INGREDIENTS | TYR, MC1R, SYMPK | PTPN1 1477/4885NOS2 36/4885CALM1 3424/4885 |
| US-10017442-B2 | Method of using dihydro-resveratrol or its stilbenoid derivatives and/or chemical variants in treatment of tumorous pathologies | VHL, ETV1, DHODH | PTPN1 3235/4885NOS2 2503/4885CALM1 2833/4885 |
| US-20180118647-A1 | Method of Using dihydro-resveratrol or its stilbenoid derivatives and/or chemical variants in treatment of tumorous pathologies | VHL, ETV1, DHODH | PTPN1 3235/4885NOS2 2503/4885CALM1 2833/4885 |
| US-10188590-B2 | Skin-protection composition containing Dendrobium-based ingredients | TYR, MC1R, SYMPK | PTPN1 1622/4885NOS2 12/4885CALM1 3346/4885 |
| US-20170057896-A1 | Method of Using dihydro-resveratrol or its stilbenoid derivatives and/or chemical variants in treatments of fibrotic and diabetic conditions | RNASE1, KRAS, DPP3 | PTPN1 2402/4885NOS2 3390/4885CALM1 4300/4885 |
| US-10351500-B2 | Method of using of dihydro-resveratrol or its stilbenoid derivatives and/or chemical variants as antimicrobial agents | DPM1, SUCLG1, VDR | PTPN1 2676/4885NOS2 3918/4885CALM1 854/4885 |
| US-20170290782-A1 | Method of Using dihydro-resveratrol or its stilbenoid derivatives and/or chemical variants in treatments of fibrotic and diabetic conditions | RNASE1, IAPP, DPP4 | PTPN1 1883/4885NOS2 3011/4885CALM1 4394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.