Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954743 | 0.86 | PTGES (0.39) | PTGESKMT2AMAPTMEN1MAPK1 | |
| SCHEMBL9957900 | 0.84 | DPP4 (0.37) | PTGESKMT2AMAPTMEN1MRGPRX4 | |
| SCHEMBL166893 | 0.83 | KDM4E (0.41) | KMT2AKDM4EMAPTMEN1ATM | |
| SCHEMBL482900 | 0.83 | TSHR (0.40) | PTGESKMT2AMAPTMEN1MRGPRX4 | |
| SCHEMBL1138229 | 0.79 | NPC1 (0.41) | KMT2AMEN1MRGPRX4PDE10ADPP4 | |
| SCHEMBL337620 | 0.79 | NPC1 (0.41) | KMT2AMEN1MRGPRX4PDE10ADPP4 | |
| SCHEMBL166029 | 0.79 | NPC1 (0.41) | KMT2AMEN1MRGPRX4PDE10ADPP4 | |
| SCHEMBL16798762 | 0.79 | MAPT (0.33) | PTGESKMT2AKDM4EMAPTMEN1 | |
| SCHEMBL4443316 | 0.77 | MEN1 (0.33) | KMT2AKDM4EMAPTMEN1ATM | |
| SCHEMBL1273638 | 0.76 | PTGES (0.36) | PTGESKMT2AMEN1DPP4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017112852-A1 | MODIFIED POLYETHYLENEIMINES AND USES THEREOF | Preceres Inc. (US) | 2017-06-29 | — | — | WO | disclosed |
| WO-2017100744-A1 | AMINOLIPIDOIDS AND USES THEREOF | Preceres Inc. (US) | 2017-06-15 | — | — | WO | disclosed |
| WO-2016036966-A1 | HYDRAZINYL LIPIDOIDS AND USES THEREOF | Preceres Inc. (US) | 2016-03-10 | — | — | WO | disclosed |