SCHEMBL166029

SCHEMBL166029

C/C(=N/OCc1cccc(C)n1)c1ccc(Cl)c(CN(C)C(=O)O)c1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
PPARG P37231 9/20 0.40
PPARA Q07869 8/20 0.40
PDE10A Q9Y233 1/20 0.37
DPP4 P27487 1/20 0.35
PPARD Q03181 2/20 0.35
MRGPRX4 Q96LA9 2/20 0.34
MEN1 O00255 1/20 0.34
OPRM1 P35372 1/20 0.34
OPRD1 P41143 1/20 0.34
KMT2A Q03164 1/20 0.34
PTGS2 P35354 1/20 0.33
HSD17B3 P37058 1/20 0.33
NR1H4 Q96RI1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1138229 1.00 NPC1 (0.41) NPC1RAB9APPARGPPARAPDE10A
SCHEMBL337620 1.00 NPC1 (0.41) NPC1RAB9APPARGPPARAPDE10A
SCHEMBL2744757 0.85 NPC1 (0.41) NPC1RAB9APPARGPPARADPP4
SCHEMBL2744761 0.85 NPC1 (0.41) NPC1RAB9APPARGPPARADPP4
SCHEMBL2778024 0.85 NPC1 (0.41) NPC1RAB9APPARGPPARADPP4
SCHEMBL4667781 0.83 NPSR1 (0.40) NPC1RAB9APPARGPPARADPP4
SCHEMBL4667786 0.83 NPSR1 (0.40) NPC1RAB9APPARGPPARADPP4
SCHEMBL28700468 0.83 DPP4 (0.40) NPC1RAB9APPARGPPARAPDE10A
SCHEMBL29726893 0.83 DPP4 (0.40) NPC1RAB9APPARGPPARAPDE10A
Pyribencarb SCHEMBL18875 0.82 NPC1 (0.39) NPC1RAB9APPARGPPARADPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11827897-B2 Agricultural compositions and related methods FLAGSHIP PIONEERING INNOVATIONS VI, LLC (US) 2023-11-28 US claimed
EP-3510869-A1 COMBINATIONS COMPRISING A FUNGICIDAL STRAIN AND AN ACTIVE COMPOUND Bayer Cropscience LP (US) 2019-07-17 EP claimed
EP-2489262-B1 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2018-11-14 EP claimed
US-20160183537-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION 2016-06-30 US claimed
US-20160186273-A1 BACILLUS AMYLOLIQUEFACIENS RTI301 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION 2016-06-30 US claimed
US-8153819-B2 Fungicidal mixtures comprising substituted 1-methylpyrazol-4-ylcarboxanilides BASF SE (DE) 2012-04-10 US claimed
EP-2324710-A1 Combinations comprising a fungicidal strain and at least one additional fungicide BASF SE (DE) 2011-05-25 EP claimed
EP-2322039-A1 Combinations comprising a fungicidal strain and at least one additional fungicide BASF SE (DE) 2011-05-18 EP claimed
EP-2319320-A1 Combinations comprising a fungicidal strain and at least one additional fungicide BASF SE (DE) 2011-05-11 EP claimed
EP-2319319-A1 Combinations comprising a fungicidal strain and at least one additional fungicide BASF SE (DE) 2011-05-11 EP claimed
EP-2292098-A1 Combinations comprising a fungicidal strain and at least one additional fungicide BASF SE (DE) 2011-03-09 EP claimed
EP-2292099-A1 Combinations comprising a fungicidal strain and at least one additional fungicide BASF SE (DE) 2011-03-09 EP claimed
US-20100273649-A1 Fungicidal Mixtures III BASF SE (DE) 2010-10-28 US claimed
EP-1942737-B1 METHOD OF INDUCING RESISTANCE TO HARMFUL FUNGI BASF SE (DE) 2010-03-03 EP claimed
US-20100022389-A1 Pesticidal Mixtures BASF SE (DE) 2010-01-28 US claimed
US-12409137-B2 Modification of plant messenger packs with charged lipids FLAGSHIP PIONEERING INNOVATIONS VI, LLC (US) 2025-09-09 US disclosed
US-20250002941-A1 A BACTERIA-DERIVED LIPID COMPOSITION AND USE THEREOF SAIL BIOMEDICINES, INC. 2025-01-02 US disclosed
US-20100022389-A1 Pesticidal Mixtures BASF SE (DE) 2010-01-28 US disclosed
WO-2009133166-A2 IMPROVED MICROEMULSION HAVING WIDE APPLICATION RANGE BASF SE (DE) 2009-11-05 WO disclosed
US-20080188493-A1 5,6-Dialkyl-7-Aminoazolopyrimidines, Their Preparation and Their Use For Controlling Harmful Fungi, and Compositions Comprising These Compounds BASF AKTIENGESELLSCHAFT (DE) 2008-08-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100022389-A1 Pesticidal Mixtures AADAC, CTRL, AAAS NPC1 3344/4885RAB9A 2436/4885PPARG 2456/4885
US-20160186273-A1 BACILLUS AMYLOLIQUEFACIENS RTI301 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE BTF3, MYB, AGXT NPC1 4630/4885RAB9A 2307/4885PPARG 1966/4885
US-20100273649-A1 Fungicidal Mixtures III CBR3, CBR1, NOX3 NPC1 993/4885RAB9A 1561/4885PPARG 2657/4885
US-20080188493-A1 5,6-Dialkyl-7-Aminoazolopyrimidines, Their Preparation and Their Use For Controlling Harmful Fungi, and Compositions Comprising These Compounds HDHD5, AGPS, DPM1 NPC1 2919/4885RAB9A 3275/4885PPARG 4356/4885
US-20160183537-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE MYB, BTF3, NRDC NPC1 4818/4885RAB9A 4301/4885PPARG 2010/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.