Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 16/20 | 0.58 |
| ▸ | NPY1R | P25929 | 10/20 | 0.58 |
| ▸ | NPY5R | Q15761 | 9/20 | 0.58 |
| ▸ | NPY2R | P49146 | 6/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.53 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.53 |
| ▸ | PTPN9 | P43378 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1662115 | 0.96 | NPY4R (0.56) | NPY4RNPY1RNPY5RNPY2RPTPN1 | |
| SCHEMBL1661913 | 0.87 | ROCK2 (0.52) | PTPN1PTPN2 | |
| SCHEMBL7532875 | 0.83 | KISS1R (0.54) | NPY4RNPY1RNPY5RNPY2RPTPN1 | |
| SCHEMBL17495218 | 0.83 | PTPN1 (0.49) | NPY4RNPY1RNPY5RNPY2RPTPN1 | |
| SCHEMBL17359203 | 0.82 | NPY4R (0.68) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL12794641 | 0.82 | NPY4R (0.68) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL18951648 | 0.82 | NPY4R (0.68) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL17356289 | 0.82 | NPY4R (0.68) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL13563457 | 0.82 | NPY4R (0.68) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29641080 | 0.81 | NPY4R (0.80) | NPY4RNPY1RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011048390-A2 | GADD45BETA TARGETING AGENTS | IMPERIAL INNOVATIONS LIMITED (GB) | 2011-04-28 | — | — | WO | claimed |
| US-20140128330-A1 | METHOD OF DIAGNOSIS AND PROGNOSIS | IMPERIAL INNOVATIONS LIMITED (GB) | 2014-05-08 | — | — | US | disclosed |
| WO-2011048390-A2 | GADD45BETA TARGETING AGENTS | IMPERIAL INNOVATIONS LIMITED (GB) | 2011-04-28 | — | — | WO | disclosed |