Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.52 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.52 |
| ▸ | HPGDS | O60760 | 4/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | APC | P25054 | 3/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1662115 | 0.92 | NPY4R (0.56) | PTPN1PTPN2 | |
| SCHEMBL1660331 | 0.87 | NPY4R (0.58) | PTPN1PTPN2 | |
| SCHEMBL1661251 | 0.84 | ROCK2 (0.51) | ROCK2ROCK1HPGDSPTPN1PTPN2 | |
| SCHEMBL14099818 | 0.81 | KISS1R (0.57) | LNPEPERAP1ERAP2 | |
| SCHEMBL18334878 | 0.79 | MME (0.60) | LNPEPERAP1ERAP2MMEFOLH1 | |
| SCHEMBL28299473 | 0.78 | CA2 (0.56) | ROCK2ROCK1PTPN1 | |
| SCHEMBL1661910 | 0.78 | CTSL (0.65) | PTPN1APCMME | |
| SCHEMBL1661176 | 0.78 | CTSL (0.65) | PTPN1APCMME | |
| SCHEMBL34461857 | 0.77 | CA2 (0.55) | MMP2FOLH1 | |
| SCHEMBL6868451 | 0.74 | MMP2 (0.61) | HPGDSPTPN1PTPN2LNPEPERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011048390-A2 | GADD45BETA TARGETING AGENTS | IMPERIAL INNOVATIONS LIMITED (GB) | 2011-04-28 | — | — | WO | claimed |
| WO-2011048390-A2 | GADD45BETA TARGETING AGENTS | IMPERIAL INNOVATIONS LIMITED (GB) | 2011-04-28 | — | — | WO | disclosed |