⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15373296 | 0.94 | — | — | |
| SCHEMBL16603858 | 0.94 | MEN1 (0.30) | — | |
| SCHEMBL16603799 | 0.93 | ALOX5 (0.30) | — | |
| SCHEMBL16603823 | 0.90 | — | — | |
| SCHEMBL16603853 | 0.89 | — | — | |
| SCHEMBL16603760 | 0.88 | BCHE (0.31) | — | |
| SCHEMBL17428058 | 0.88 | NAAA (0.32) | — | |
| SCHEMBL16603824 | 0.88 | NAAA (0.30) | — | |
| SCHEMBL16603839 | 0.88 | — | — | |
| SCHEMBL16603830 | 0.88 | RIPK1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9439422-B2 | Use of macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2016-09-13 | — | — | US | disclosed |
| US-9439422-B2 | Use of macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2016-09-13 | — | — | US | disclosed |
| US-9179674-B2 | Macrocyclic picolinamide compounds with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2015-11-10 | — | — | US | disclosed |
| US-9179674-B2 | Macrocyclic picolinamide compounds with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2015-11-10 | — | — | US | disclosed |
| WO-2015050818-A1 | MACROCYCLIC PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2015-04-09 | — | — | WO | disclosed |
| WO-2015050819-A1 | USE OF MACROCYLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2015-04-09 | — | — | WO | disclosed |
| US-20150094339-A1 | MACROCYCLIC PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC | 2015-04-02 | — | — | US | disclosed |
| US-20150094339-A1 | MACROCYCLIC PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC | 2015-04-02 | — | — | US | disclosed |
| US-20150094340-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC | 2015-04-02 | — | — | US | disclosed |
| US-20150094340-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC | 2015-04-02 | — | — | US | disclosed |