SCHEMBL16604200

SCHEMBL16604200

Brc1ccc(-c2cc3ccc4cc(-c5cccc6ccccc56)cc5ccc(c2)c3c45)c2ccccc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.45
CA12 O43570 5/20 0.41
CA1 P00915 5/20 0.41
CA2 P00918 5/20 0.41
CA9 Q16790 5/20 0.41
ERBB2 P04626 1/20 0.41
FYN P06241 1/20 0.41
MAOA P21397 1/20 0.41
ACHE P22303 1/20 0.41
AHR P35869 1/20 0.41
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
CES1 P23141 1/20 0.39
DNMT1 P26358 1/20 0.39
FNTA P49354 1/20 0.38
FNTB P49356 1/20 0.38
MCL1 Q07820 1/20 0.38
ACMSD Q8TDX5 1/20 0.38
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15731070 0.93 CYP1A2 (0.47) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL31505497 0.88 CYP1A2 (0.50) CYP1A2CA12CA1CA2CA9
SCHEMBL16557787 0.86 NPSR1 (0.44) CYP1A2CA12CA1CA2CA9
SCHEMBL27697459 0.86 CYP1A2 (0.53) CYP1A2CA12CA1CA2CA9
SCHEMBL16792034 0.82 CA12 (0.53) CYP1A2CA12CA1CA2CA9
SCHEMBL947346 0.82 CYP1A2 (0.52) CYP1A2CA12CA1CA2CA9
SCHEMBL29490404 0.82 CYP1A2 (0.52) CYP1A2CA12CA1CA2CA9
SCHEMBL19911017 0.79 ALDH1A1 (0.47) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL17849708 0.79 CYP1A2 (0.37) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL12192912 0.79 CA12 (0.47) CYP1A2CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9680106-B2 Pyrene-based compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-13 US disclosed
US-9680106-B2 Pyrene-based compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-13 US disclosed
US-20150090967-A1 PYRENE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-04-02 US disclosed
US-20150090967-A1 PYRENE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-04-02 US disclosed