SCHEMBL17849708

SCHEMBL17849708

Brc1ccc(-c2cc3c4c(ccc5cccc(c54)C34c3ccccc3-c3ccccc34)c2)c2ccccc12

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.37
ERBB2 P04626 1/20 0.33
FYN P06241 1/20 0.33
MAOA P21397 1/20 0.33
ACHE P22303 1/20 0.33
AHR P35869 1/20 0.33
CES1 P23141 1/20 0.32
DHFR P00374 3/20 0.31
TYMS P04818 2/20 0.31
ALDH1A1 P00352 1/20 0.31
THRB P10828 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31
CYP1B1 Q16678 1/20 0.30
HKDC1 Q2TB90 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17849702 0.83 CYP1A2 (0.35) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL15731070 0.82 CYP1A2 (0.47) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL17849687 0.80 SLC6A3 (0.35) ACHEDHFRTYMSALDH1A1HPGD
SCHEMBL17849709 0.79 TYMS (0.34) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL16604200 0.79 CYP1A2 (0.45) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL12927698 0.78 NPSR1 (0.44) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL19980414 0.76 CYP1A2 (0.47) CYP1A2ALDH1A1CYP1B1HKDC1
SCHEMBL30343464 0.76 CYP1A2 (0.47) CYP1A2ALDH1A1CYP1B1HKDC1
SCHEMBL22646598 0.75 ALDH1A1 (0.48) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL15909679 0.74 LPL (0.38) CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9371270-B2 Compound for organic light-emitting device and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-21 US disclosed
US-9371270-B2 Compound for organic light-emitting device and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-21 US disclosed