SCHEMBL1660424

SCHEMBL1660424

CCCCc1ccc(-c2nc(-c3ccc(Br)cc3)nc(-c3ccc(Br)cc3)n2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.59
SMN1; SMN2 Q16637 4/20 0.59
NPC1 O15118 3/20 0.59
NFKB1 P19838 2/20 0.59
NFKB2 Q00653 2/20 0.59
RELA Q04206 2/20 0.59
MAPK1 P28482 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
ALDH1A1 P00352 3/20 0.54
MAPT P10636 3/20 0.54
S1PR1 P21453 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
RARB P10826 6/20 0.49
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
KDM4E B2RXH2 1/20 0.47
USP2 O75604 1/20 0.47
GAA P10253 1/20 0.47
HPGD P15428 1/20 0.47
HSD17B10 Q99714 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1659837 0.93 ALDH1A1 (0.56) RAB9ASMN1; SMN2NPC1NFKB1NFKB2
SCHEMBL12128134 0.93 ALDH1A1 (0.56) RAB9ASMN1; SMN2NPC1NFKB1NFKB2
SCHEMBL15762285 0.93 ALDH1A1 (0.56) RAB9ASMN1; SMN2NPC1NFKB1NFKB2
SCHEMBL10057499 0.92 ALDH1A1 (0.55) RAB9ASMN1; SMN2NPC1NFKB1NFKB2
SCHEMBL13539887 0.91 RAB9A (0.57) RAB9ASMN1; SMN2NPC1NFKB1NFKB2
SCHEMBL2050263 0.87 NPC1 (0.64) RAB9ASMN1; SMN2NPC1NFKB1NFKB2
SCHEMBL13539898 0.86 ALDH1A1 (0.50) RAB9ASMN1; SMN2NPC1NFKB1NFKB2
SCHEMBL17928942 0.86 ALDH1A1 (0.50) RAB9ASMN1; SMN2NPC1NFKB1NFKB2
SCHEMBL16784541 0.86 ALDH1A1 (0.50) RAB9ASMN1; SMN2NPC1NFKB1NFKB2
SCHEMBL13539888 0.85 ALDH1A1 (0.62) RAB9ASMN1; SMN2NPC1NFKB1NFKB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9048442-B2 Composition containing a metal complex and organic compound, and light-emitting element using said compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-06-02 US disclosed
EP-2305772-B1 COMPOSITION CONTAINING A METAL COMPLEX AND ORGANIC COMPOUND, AND LIGHT EMITTING ELEMENT USING SAID COMPOUND SUMITOMO CHEMICAL CO (JP) 2015-05-20 EP disclosed
US-20110279028-A1 Polymer, Its Preparation and Uses O'DELL RICHARD (DE) 2011-11-17 US disclosed
US-20110279028-A1 Polymer, Its Preparation and Uses O'DELL RICHARD (DE) 2011-11-17 US disclosed
US-20110114890-A1 COMPOSITION CONTAINING A METAL COMPLEX AND ORGANIC COMPOUND, AND LIGHT-EMITTING ELEMENT USING SAID COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-05-19 US disclosed
EP-2305772-A1 COMPOSITION CONTAINING A METAL COMPLEX AND ORGANIC COMPOUND, AND LIGHT EMITTING ELEMENT USING SAID COMPOUND Sumitomo Chemical Company, Limited (JP) 2011-04-06 EP disclosed