SCHEMBL16605160

SCHEMBL16605160

Cc1cccc(-c2ccc(-c3ccc(C)cc3CCC(=O)O)cc2C(F)F)c1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ FFAR1 O14842 10/20 0.47
▸ FFAR4 Q5NUL3 5/20 0.47
▸ PTGER4 P35408 5/20 0.46
▸ PTGER3 P43115 5/20 0.46
▸ PTGER1 P34995 4/20 0.46
▸ PTGER2 P43116 4/20 0.46
▸ AKR1C3 P42330 1/20 0.41
▸ AKR1C2 P52895 1/20 0.41
▸ MME P08473 1/20 0.41
▸ RXRA P19793 2/20 0.41
▸ RXRB P28702 2/20 0.41
▸ RXRG P48443 2/20 0.41
▸ NR4A2 P43354 1/20 0.41
▸ CNR2 P34972 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1892518 0.92 FFAR1 (0.47) FFAR1FFAR4PTGER4PTGER3PTGER1
SCHEMBL1894408 0.89 FFAR1 (0.50) FFAR1FFAR4PTGER4PTGER3PTGER1
SCHEMBL16605163 0.84 FFAR1 (0.50) FFAR1FFAR4PTGER4PTGER3PTGER1
SCHEMBL16605158 0.84 FFAR1 (0.54) FFAR1FFAR4PTGER4PTGER3PTGER1
SCHEMBL15948945 0.82 FFAR1 (0.48) FFAR1FFAR4PTGER4PTGER3PTGER1
SCHEMBL1891473 0.80 CYP4F2 (0.39) FFAR1FFAR4AKR1C3AKR1C2CNR2
SCHEMBL35843123 0.80 CYP4F2 (0.39) FFAR1FFAR4AKR1C3AKR1C2CNR2
SCHEMBL1802536 0.80 FFAR1 (0.48) FFAR1FFAR4PTGER4PTGER3PTGER1
SCHEMBL38660342 0.80 FFAR1 (0.48) FFAR1FFAR4PTGER4PTGER3PTGER1
SCHEMBL35843129 0.78 MTNR1A (0.44) FFAR1FFAR4AKR1C3AKR1C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170204197-A1 Goodpasture Antigen Binding Protein Detection and Inhibition and its Use in Diabetes FIBROSTATIN S L (ES) 2017-07-20 — — US disclosed
US-20150320730-A1 GPBP-1 inhibition and its therapeutic use FIBROSTATIN, S.L. (ES) 2015-11-12 — — US disclosed
US-9066938-B2 GPBP-1 inhibition and its therapeutic use Fibrostein, S.L. (ES) 2015-06-30 — — US disclosed
US-20150093378-A1 Goodpasture Antigen Binding Protein Detection and Inhibition and its Use in Diabetes FIBROSTATIN, S.L. (ES) 2015-04-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170204197-A1 Goodpasture Antigen Binding Protein Detection and Inhibition and its Use in Diabetes CD2BP2, SAP30BP, LY96 FFAR1 3034/4885FFAR4 2309/4885PTGER4 2192/4885
US-20150093378-A1 Goodpasture Antigen Binding Protein Detection and Inhibition and its Use in Diabetes CD2BP2, SAP30BP, LY96 FFAR1 3034/4885FFAR4 2309/4885PTGER4 2192/4885
US-20150320730-A1 GPBP-1 inhibition and its therapeutic use ABCC1, ABCC8, ABCB1 FFAR1 2553/4885FFAR4 3802/4885PTGER4 2556/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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