SCHEMBL1660862

SCHEMBL1660862

CCc1cccc(O)c1N

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.56
GABRB2 P47870 2/20 0.56
G6PD P11413 1/20 0.47
CASP7 P55210 1/20 0.47
CASP6 P55212 1/20 0.47
IAPP P10997 3/20 0.43
ANPEP P15144 1/20 0.42
DPP4 P27487 1/20 0.42
HSPA5 P11021 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
DAO P14920 2/20 0.41
DDO Q99489 1/20 0.41
TAAR1 Q96RJ0 1/20 0.40
AKR1B1 P15121 1/20 0.40
BID P55957 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL27302905 0.98 GABRA1 (0.54) GABRA1GABRB2G6PDCASP7CASP6
SCHEMBL10438966 0.84 IAPP (0.44) GABRA1GABRB2G6PDCASP7CASP6
SCHEMBL29875751 0.83 TAAR1 (0.50) GABRA1GABRB2G6PDCASP7CASP6
SCHEMBL1332031 0.83 GABRA1 (0.55) GABRA1GABRB2
SCHEMBL262868 0.83 GABRA1 (0.55) GABRA1GABRB2
SCHEMBL564903 0.81 HSPA5 (0.56) GABRA1GABRB2G6PDCASP7CASP6
SCHEMBL31621098 0.81 HSPA5 (0.56) GABRA1GABRB2G6PDCASP7CASP6
SCHEMBL6883028 0.81 BID (0.51) IAPPBIDBCL2L1MCL1BAK1
SCHEMBL28967677 0.80 GABRA1 (0.52) GABRA1GABRB2
Hydrochloric Acid SCHEMBL625383 0.80 GABRA1 (0.52) GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025099118-A1 NEW TELESCOPING SYNTHESES OF 5-ETHYL-2-AMINO-PHENOL WELLA GERMANY GMBH (DE) 2025-05-15 WO claimed
WO-2025099118-A1 NEW TELESCOPING SYNTHESES OF 5-ETHYL-2-AMINO-PHENOL WELLA GERMANY GMBH (DE) 2025-05-15 WO disclosed
WO-2024219864-A1 NOVEL COMPOUND EXHIBITING SETDB1 INHIBITORY ACTIVITY, AND USE THEREOF 주식회사 넷타겟 2024-10-24 WO disclosed
EP-3941424-A1 HAIR COLORANT COMPOSITIONS Wella International Operations Switzerland Sàrl (CH) 2022-01-26 EP disclosed
US-10920017-B2 Polyimide resin and resin composition KANEKA CORPORATION (JP) 2021-02-16 US disclosed
US-20190263968-A1 POLYIMIDE RESIN AND RESIN COMPOSITION KANEKA CORPORATION (JP) 2019-08-29 US disclosed
US-10160722-B2 Method for producing perfluoroalkanesulfonyl phenol compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-12-25 US disclosed
US-20180290970-A1 METHOD FOR PRODUCING PERFLUOROALKANESULFONYL PHENOL COMPOUNDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-10-11 US disclosed
US-9957241-B2 Aromatic diamine, an intermediate therefor, a method for producing the aromatic diamine, and a method for producing the intermediate therefor SEIKA CORPORATION (JP) 2018-05-01 US disclosed
US-20180079732-A1 AROMATIC DIAMINE, AN INTERMEDIATE THEREFOR, A METHOD FOR PRODUCING THE AROMATIC DIAMINE, AND A METHOD FOR PRODUCING THE INTERMEDIATE THEREFOR SEIKA CORPORATION (JP) 2018-03-22 US disclosed
US-6461390-B1 Process for making 2-aminomethyl-1, 4-diaminobenzene and its salts and compositions and methods for dyeing keratin fibers using same WELLA AKTIENGESELLSCHAFT (DE) 2002-10-08 US disclosed
EP-0275139-B1 ASSAY METHOD USING PARTICLES WITH ASSOCIATED FLUORESCER SYNTEX (U.S.A.) INC. (US) 1992-04-15 EP disclosed
EP-0439885-A1 Oil soluble dispersant additives modified with monoepoxy monounsaturated compounds EXXON CHEMICAL PATENTS INC. (US) 1991-08-07 EP disclosed
EP-0400864-A2 Improved branched amido-amine dispersant additives EXXON CHEMICAL PATENTS INC. (US) 1990-12-05 EP disclosed
EP-0391651-A2 Improved low ash lubricant composition for internal combustion engines EXXON CHEMICAL PATENTS INC. (US) 1990-10-10 EP disclosed
EP-0391649-A2 Improved ashless lubricant compositions for internal combustion engines EXXON CHEMICAL PATENTS INC. (US) 1990-10-10 EP disclosed
EP-0357217-A2 Ethylene alpha-olefin copolymer substituted amino phenol mannich base lubricant dispersant additives EXXON CHEMICAL PATENTS INC. (US) 1990-03-07 EP disclosed
US-4891324-A FLUORIMETRY SYNTEX (U.S.A.) INC. (US) 1990-01-02 US disclosed
EP-0275139-A2 Assay method using particles with associated fluorescer SYNTEX (U.S.A.) INC. (US) 1988-07-20 EP disclosed
US-4443371-A LEATHER, PAPER ALTHOUSE TERTRE, S.A. (BE) 1984-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180079732-A1 AROMATIC DIAMINE, AN INTERMEDIATE THEREFOR, A METHOD FOR PRODUCING THE AROMATIC DIAMINE, AND A METHOD FOR PRODUCING THE INTERMEDIATE THEREFOR WEE1, WEE2, WASF2 GABRA1 409/4885GABRB2 640/4885G6PD 3783/4885
US-10160722-B2 Method for producing perfluoroalkanesulfonyl phenol compounds ACOX3, PEX3, PAOX GABRA1 2095/4885GABRB2 2788/4885G6PD 2561/4885
US-20180290970-A1 METHOD FOR PRODUCING PERFLUOROALKANESULFONYL PHENOL COMPOUNDS ACOX3, PEX3, PAOX GABRA1 2095/4885GABRB2 2788/4885G6PD 2561/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.