SCHEMBL564903

SCHEMBL564903

Nc1c(O)cccc1Cc1cccc(O)c1N

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 0.56
G6PD P11413 1/20 0.45
CASP7 P55210 1/20 0.45
CASP6 P55212 1/20 0.45
TAAR1 Q96RJ0 1/20 0.43
IDO1 P14902 2/20 0.41
TSHR P16473 2/20 0.40
ALOX15 P16050 2/20 0.40
KEAP1 Q14145 1/20 0.40
HIF1A Q16665 2/20 0.39
CYP2D6 P10635 1/20 0.39
TDP1 Q9NUW8 2/20 0.39
ADAMTS4 O75173 1/20 0.39
ALDH1A1 P00352 1/20 0.39
EGFR P00533 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
LMNA P02545 1/20 0.39
FYN P06241 1/20 0.39
MMP2 P08253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31621098 1.00 HSPA5 (0.56) HSPA5G6PDCASP7CASP6TAAR1
SCHEMBL11160370 0.93 HSPA5 (0.70) HSPA5G6PDCASP7CASP6TAAR1
SCHEMBL29875751 0.87 TAAR1 (0.50) HSPA5G6PDCASP7CASP6TAAR1
SCHEMBL563903 0.85 BCL2 (0.55) HSPA5G6PDCASP7CASP6ALOX15
SCHEMBL21010896 0.83 KEAP1 (0.66) HSPA5TAAR1IDO1KEAP1ALDH1A1
SCHEMBL31033256 0.83 G6PD (0.43) HSPA5G6PDCASP7CASP6TAAR1
SCHEMBL3167058 0.83 G6PD (0.43) HSPA5G6PDCASP7CASP6TAAR1
SCHEMBL27957545 0.83 TAAR1 (0.46) HSPA5G6PDCASP7CASP6TAAR1
SCHEMBL18469204 0.81 TAAR1 (0.68) G6PDCASP7CASP6TAAR1ALOX15
SCHEMBL1660862 0.81 GABRA1 (0.56) HSPA5G6PDCASP7CASP6TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8674029-B2 Method of preparing stabilized polymeric systems using polymeric peroxides Sunocs LLC (US) 2014-03-18 US disclosed
US-20120035307-A1 PROCESS FOR MAKING STABLIZED POLYMERIC SYSTEMS WITH NANOSTRUCTURES SONG CHENGQIAN (US) 2012-02-09 US disclosed
US-20120035315-A1 METHOD OF PREPARING STABLIZED POLYMERIC SYSTEMS USING POLYMERIC PEROXIDES SONG CHENGQIAN (US) 2012-02-09 US disclosed
US-20110311871-A1 NEGATIVE ELECTRODE FOR LITHIUM SECONDARY BATTERIES AND LITHIUM SECONDARY BATTERY SANYO ELECTRIC CO., LTD. (JP) 2011-12-22 US disclosed
US-7498467-B2 Antioxidant and bisaminophenol derivative IDEMITSU KOSAN CO., LTD. (JP) 2009-03-03 US disclosed
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN CO., LTD. (JP) 2008-07-03 US disclosed
US-20060208227-A1 Antioxidant and bisaminophenol derivative IDEMITSU LOSAN CO., LTD (JP) 2006-09-21 US disclosed
EP-1612254-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN COMPANY LIMITED (JP) 2006-01-04 EP disclosed
US-20040152862-A1 Optical resins and applications thereof HITACHI CHEMICAL CO., LTD. (JP) 2004-08-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE CBR1, CBR3, HMOX1 HSPA5 1968/4885G6PD 579/4885CASP7 2094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.