Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.50 |
| ▸ | NOS1 | P29475 | 3/20 | 0.50 |
| ▸ | NOS2 | P35228 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RGS12 | O14924 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1660868 | 1.00 | NOS3 (0.50) | NOS3NOS1NOS2PKMALPI | |
| SCHEMBL44126 | 0.92 | PKM (0.58) | NOS3NOS1NOS2PKMALPI | |
| SCHEMBL29401250 | 0.92 | PKM (0.58) | NOS3NOS1NOS2PKMALPI | |
| SCHEMBL268942 | 0.92 | PKM (0.58) | NOS3NOS1NOS2PKMALPI | |
| SCHEMBL44127 | 0.92 | PKM (0.58) | NOS3NOS1NOS2PKMALPI | |
| Hydrochloric Acid SCHEMBL27128716 | 0.90 | PKM (0.56) | NOS3NOS1NOS2PKMALPI | |
| Hydrochloric Acid SCHEMBL27515071 | 0.90 | PKM (0.56) | NOS3NOS1NOS2PKMALPI | |
| Hydrochloric Acid SCHEMBL26985803 | 0.90 | PKM (0.56) | NOS3NOS1NOS2PKMALPI | |
| SCHEMBL188588 | 0.90 | SLC7A5 (0.55) | NOS3NOS1NOS2PKMALPI | |
| SCHEMBL188587 | 0.90 | SLC7A5 (0.55) | NOS3NOS1NOS2PKMALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2491054-A2 | SHORT CHAIN PEPTIDOMIMETICS BASED ORALLY ACTIVE GLP-1 AGONIST AND GLUCAGON RECEPTOR ANTAGONIST | Cadila Healthcare Limited (IN) | 2012-08-29 | — | — | EP | disclosed |
| WO-2011048614-A2 | SHORT CHAIN PEPTIDOMIMETICS BASED ORALLY ACTIVE GLP-1 AGONIST AND GLUCAGON RECEPTOR ANTAGONIST | CADILA HEALTHCARE LIMITED (IN) | 2011-04-28 | — | — | WO | disclosed |
| EP-2084182-A2 | ANTIDIABETIC COMPOUNDS | Cadila Healthcare Limited (IN) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008062457-A2 | ANTIDIABETIC COMPOUNDS | CADILA HEALTHCARE LIMITED (IN) | 2008-05-29 | — | — | WO | disclosed |