Sugi Predict

Sugi Predict / Compounds / SCHEMBL268942

SCHEMBL268942

SCHEMBL268942

N[C@H](Cc1ccccc1F)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PKM P14618 2/20 0.58
▸ ALPI P09923 1/20 0.58
▸ PTGS1 P23219 1/20 0.58
▸ XIAP P98170 1/20 0.58
▸ SLC7A5 Q01650 1/20 0.58
▸ NOS3 P29474 3/20 0.57
▸ NOS1 P29475 3/20 0.57
▸ NOS2 P35228 3/20 0.57
▸ PTPN1 P18031 1/20 0.56
▸ MAPT P10636 3/20 0.53
▸ USP2 O75604 2/20 0.53
▸ HIF1A Q16665 2/20 0.53
▸ KDM4E B2RXH2 2/20 0.53
▸ MEN1 O00255 2/20 0.53
▸ LMNA P02545 2/20 0.53
▸ BLM P54132 2/20 0.53
▸ PMP22 Q01453 2/20 0.53
▸ KMT2A Q03164 2/20 0.53
▸ ALDH1A1 P00352 2/20 0.53
▸ RECQL P46063 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL44126 1.00 PKM (0.58) PKMALPIPTGS1XIAPSLC7A5
SCHEMBL29401250 1.00 PKM (0.58) PKMALPIPTGS1XIAPSLC7A5
SCHEMBL44127 1.00 PKM (0.58) PKMALPIPTGS1XIAPSLC7A5
Hydrochloric Acid SCHEMBL27515071 0.98 PKM (0.56) PKMALPIPTGS1XIAPSLC7A5
Hydrochloric Acid SCHEMBL27128716 0.98 PKM (0.56) PKMALPIPTGS1XIAPSLC7A5
Hydrochloric Acid SCHEMBL26985803 0.98 PKM (0.56) PKMALPIPTGS1XIAPSLC7A5
SCHEMBL1660868 0.92 NOS3 (0.50) PKMALPIPTGS1XIAPSLC7A5
SCHEMBL1660865 0.92 NOS3 (0.50) PKMALPIPTGS1XIAPSLC7A5
SCHEMBL13971424 0.86 SLC7A5 (0.69) PKMALPIPTGS1XIAPSLC7A5
SCHEMBL9164980 0.86 SLC7A5 (0.69) PKMALPIPTGS1XIAPSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 384 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4696700-A1 LONG-ACTING K-OPIOID RECEPTOR AGONIST Chengdu Aoda Biotechnology Co., Ltd (CN) 2026-02-18 — — EP claimed
EP-4696699-A1 ? OPIOID RECEPTOR AGONIST AND USE THEREOF Chengdu Aoda Biotechnology Co., Ltd. (CN) 2026-02-18 — — EP claimed
CN-119899240-A Kappa opioid receptor agonist and application thereof 成都奥达生物科技有限公司 2025-04-29 — — CN claimed
CN-119390765-A Kappa opioid receptor agonist and application thereof 成都奥达生物科技有限公司 2025-02-07 — — CN claimed
WO-2024212866-A1 LONG-ACTING K-OPIOID RECEPTOR AGONIST 成都奥达生物科技有限公司 2024-10-17 — — WO claimed
WO-2024212865-A1 κ OPIOID RECEPTOR AGONIST AND USE THEREOF 成都奥达生物科技有限公司 2024-10-17 — — WO claimed
CN-118772231-A Kappa opioid receptor agonist and application thereof 成都奥达生物科技有限公司 2024-10-15 — — CN claimed
US-9695191-B2 Conformationally constrained, fully synthetic macrocyclic compounds POLYPHOR AG (CH) 2017-07-04 — — US claimed
EP-2462147-B1 CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS POLYPHOR AG (CH) 2014-11-12 — — EP claimed
US-20120202821-A1 CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS POLYPHOR AG (CH) 2012-08-09 — — US claimed
US-20260083834-A1 CsgA-DERIVED NANOSTRUCTURES AND USES THEREOF FOR ANTIGEN DELIVERY TRANSFERT PLUS LP (CA) 2026-03-26 — — US disclosed
EP-4696700-A1 LONG-ACTING K-OPIOID RECEPTOR AGONIST Chengdu Aoda Biotechnology Co., Ltd (CN) 2026-02-18 — — EP disclosed
EP-4696699-A1 ? OPIOID RECEPTOR AGONIST AND USE THEREOF Chengdu Aoda Biotechnology Co., Ltd. (CN) 2026-02-18 — — EP disclosed
US-20250367300-A1 Nanomaterial and Methods of Use Thereof UNIVERSITY OF CONNECTICUT (US) 2025-12-04 — — US disclosed
US-20250302971-A1 Therapeutic Nanomaterials UNIV CONNECTICUT (US) 2025-10-02 — — US disclosed
WO-2007137080-A2 COMPOUNDS AND COMPOSITIONS AS CHANNEL ACTIVATING PROTEASE INHIBITORS IRM LLC (BM) 2007-11-29 — — WO disclosed
US-20070275906-A1 Compounds and Compositions as Channel Activating Protease Inhibitors IRM LLC (BM) 2007-11-29 — — US disclosed
WO-2007062664-A2 ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES NUEVOLUTION A/S (DK) 2007-06-07 — — WO disclosed
WO-2007015767-A1 PYRIDINE DERIVATIVES AS DIPEPTEDYL PEPTIDASE INHIBITORS ELI LILLY AND COMPANY (US) 2007-02-08 — — WO disclosed
WO-2006113837-A2 INHIBITORS OF AKT ACTIVITY SMITHKLINE BEECHAM CORPORATION (US) 2006-10-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250302971-A1 Therapeutic Nanomaterials TIE1, TEKT1, POLRMT PKM 1858/4885ALPI 4083/4885PTGS1 3983/4885
US-20120202821-A1 CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS HTR2B, MC1R, HTR1A PKM 2553/4885ALPI 2014/4885PTGS1 109/4885
US-20250367300-A1 Nanomaterial and Methods of Use Thereof EPCAM, CD47, JAK2 PKM 1314/4885ALPI 563/4885PTGS1 1907/4885
US-20260083834-A1 CsgA-DERIVED NANOSTRUCTURES AND USES THEREOF FOR ANTIGEN DELIVERY VSIG8, MICA, CD74 PKM 4604/4885ALPI 2844/4885PTGS1 3808/4885
US-20070275906-A1 Compounds and Compositions as Channel Activating Protease Inhibitors PRSS1, PRSS8, PRSS2 PKM 4421/4885ALPI 3334/4885PTGS1 266/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.