Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CTRB1 | P17538 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALPG | P10696 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3173563 | 0.87 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL3169238 | 0.83 | ANPEP (0.32) | — | |
| SCHEMBL7508602 | 0.81 | TRPA1 (0.31) | — | |
| SCHEMBL7539818 | 0.80 | GRIN2D (0.30) | — | |
| SCHEMBL7544995 | 0.80 | GRIN2D (0.30) | — | |
| SCHEMBL7545125 | 0.80 | GRIN2D (0.30) | — | |
| SCHEMBL28574730 | 0.80 | GRIN2D (0.30) | — | |
| SCHEMBL5476252 | 0.80 | ALPI (0.34) | MTNR1AMTNR1BALPIPKMPTGS1 | |
| SCHEMBL9716882 | 0.79 | GRIN2D (0.31) | — | |
| SCHEMBL28585391 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2490530-A1 | COMPOUNDS AND METHODS FOR TREATING BACTERIAL INFECTIONS | The Washington University (US) | 2012-08-29 | — | — | EP | disclosed |
| WO-2011050323-A1 | COMPOUNDS AND METHODS FOR TREATING BACTERIAL INFECTIONS | THE WASHINGTON UNIVERSITY (US) | 2011-04-28 | — | — | WO | disclosed |