Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | LAP3 | P28838 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7508602 | 0.85 | TRPA1 (0.31) | TRPA1 | |
| SCHEMBL7539818 | 0.84 | GRIN2D (0.30) | GRIN2DGRIN3BADRA1DADRA1AADRA1B | |
| SCHEMBL28574730 | 0.84 | GRIN2D (0.30) | GRIN2DGRIN3BADRA1DADRA1AADRA1B | |
| SCHEMBL7544995 | 0.84 | GRIN2D (0.30) | GRIN2DGRIN3BADRA1DADRA1AADRA1B | |
| SCHEMBL7545125 | 0.84 | GRIN2D (0.30) | GRIN2DGRIN3BADRA1DADRA1AADRA1B | |
| SCHEMBL9716882 | 0.83 | GRIN2D (0.31) | GRIN2DGRIN3BADRA1DADRA1AADRA1B | |
| SCHEMBL1660908 | 0.83 | MTNR1A (0.33) | — | |
| SCHEMBL5466217 | 0.79 | ANPEP (0.32) | ANPEPLAP3TRPA1GRIN2DGRIN3B | |
| SCHEMBL2045566 | 0.77 | GRIN2D (0.31) | GRIN2DGRIN3BADRA1DADRA1AADRA1B | |
| SCHEMBL8583373 | 0.77 | GRIN2D (0.31) | GRIN2DGRIN3BADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7648966-B2 | Mannose-6-phosphonate compounds for the treatment of inflammatory diseases | Pharmaxis Pty Limited (AU) | 2010-01-19 | — | — | US | disclosed |
| EP-1628987-B1 | MANNOSE-6-PHOSPHONATE COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISEASES | PHARMAXIS PTY LTD (AU) | 2009-08-19 | — | — | EP | disclosed |
| US-20070082850-A1 | Mannose-6-phosphonate compounds for the treatment of inflammatory diseases | PHARMAXIX PTY LTD (AU) | 2007-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070082850-A1 | Mannose-6-phosphonate compounds for the treatment of inflammatory diseases | PMM2, CD4, MPI | ANPEP 579/4885LAP3 2085/4885TRPA1 2710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.