Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.30 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29417721 | 0.81 | PTGDR2 (0.48) | PTGDR2SLC6A4SLC6A2MAPK1HSD17B10 | |
| SCHEMBL795719 | 0.81 | PTGDR2 (0.48) | PTGDR2SLC6A4SLC6A2MAPK1HSD17B10 | |
| SCHEMBL16607648 | 0.81 | CYP2A6 (0.40) | SLC6A4MAPK1ALDH1A1MAPTMEN1 | |
| SCHEMBL3985481 | 0.78 | TSHR (0.46) | MAPK1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL23094700 | 0.78 | ALOX15 (0.40) | ALDH1A1TSHRGFERCASP1ALOX15 | |
| SCHEMBL7667398 | 0.78 | IDO1 (0.37) | SLC6A4SLC6A2PDK2 | |
| SCHEMBL1055260 | 0.76 | PYCR1 (0.44) | NPC1RAB9A | |
| SCHEMBL30626575 | 0.76 | KDM1A (0.43) | PTGDR2SLC6A4SLC6A2USP28USP25 | |
| SCHEMBL20196946 | 0.76 | KDM1A (0.43) | PTGDR2SLC6A4SLC6A2USP28USP25 | |
| SCHEMBL8128901 | 0.75 | PTGDR2 (0.44) | PTGDR2SLC6A4SLC6A2MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015046405-A1 | ANALGESIC | 東レ株式会社 | 2015-04-02 | — | — | WO | disclosed |