Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1108653 | 0.79 | RAB9A (0.53) | RAB9AMAPTHCAR3NPC1SMN1; SMN2 | |
| SCHEMBL6645913 | 0.79 | MAPT (0.53) | RAB9AMAPTHCAR3SMN1; SMN2ACKR3 | |
| SCHEMBL10604098 | 0.78 | HCAR3 (0.59) | RAB9AMAPTHCAR3NPC1SMN1; SMN2 | |
| SCHEMBL10737266 | 0.77 | HRH3 (0.47) | RAB9AMAPTHCAR3ACKR3KMT2A | |
| Bromide SCHEMBL10609035 | 0.77 | HCAR3 (0.58) | RAB9AMAPTHCAR3NPC1SMN1; SMN2 | |
| SCHEMBL12832042 | 0.76 | RAB9A (0.52) | RAB9AMAPTHCAR3SMN1; SMN2KMT2A | |
| SCHEMBL27956734 | 0.76 | KDM4E (0.49) | RAB9AMAPTHCAR3NPC1SMN1; SMN2 | |
| SCHEMBL22265370 | 0.76 | HCAR3 (0.59) | RAB9AMAPTHCAR3ACKR3GAA | |
| SCHEMBL10293613 | 0.74 | HCAR3 (0.57) | RAB9AMAPTHCAR3SMN1; SMN2ACKR3 | |
| SCHEMBL15743947 | 0.74 | CYP2C19 (0.46) | RAB9AMAPTHCAR3NPC1ACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015048819-A1 | ANTI-ALPHAVBETA1 INTEGRIN COMPOUNDS AND METHODS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-04-02 | — | — | WO | disclosed |