SCHEMBL16610057

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18020602	0.90	PTGS2 (0.53)	PTGS2LMNAKDM4EKMT2AALDH1A1
	SCHEMBL16599395	0.89	PTGS2 (0.55)	PTGS2CYP4F2CYP4A11LMNAKDM4E
	SCHEMBL16599463	0.88	PTGS2 (0.51)	PTGS2LMNAKDM4EKMT2AALDH1A1
	SCHEMBL4965041	0.82	PTGS2 (0.60)	PTGS2CYP4F2CYP4A11LMNAKDM4E
	SCHEMBL17986190	0.82	PTGS2 (0.46)	PTGS2LMNAKDM4EKMT2AALDH1A1
	SCHEMBL4134586	0.82	PTGS2 (0.80)	PTGS2CYP4F2CYP4A11LMNAKDM4E
	SCHEMBL16610070	0.80	PTGS2 (0.44)	PTGS2LMNAKDM4EKMT2AALDH1A1
	SCHEMBL18020601	0.80	PTGS2 (0.53)	PTGS2LMNAKDM4EKMT2ACYP1A2
	SCHEMBL12536688	0.80	KMT2A (0.57)	PTGS2CYP4F2CYP4A11LMNAKDM4E
	SCHEMBL18020585	0.78	MAPT (0.47)	PTGS2CYP4F2CYP4A11LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.