SCHEMBL17986190

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17986205	0.91	PTGS2 (0.46)	PTGS2LMNAKMT2AMAPTALDH1A1
	SCHEMBL4959789	0.85	PTGS2 (0.49)	PTGS2KDM4ELMNAKMT2AMAPT
	SCHEMBL29454034	0.85	PTGS2 (0.64)	PTGS2KDM4ELMNAKMT2AMAPT
	SCHEMBL4138781	0.85	PTGS2 (0.64)	PTGS2KDM4ELMNAKMT2AMAPT
	SCHEMBL18020602	0.83	PTGS2 (0.53)	PTGS2KDM4ELMNAKMT2AMAPT
	SCHEMBL16610057	0.82	PTGS2 (0.55)	PTGS2KDM4ELMNAKMT2AMAPT
	SCHEMBL18020588	0.81	GAA (0.48)	KDM4EKMT2AMAPTALDH1A1CA12
	SCHEMBL17986294	0.81	PTGS2 (0.47)	PTGS2KDM4ELMNAKMT2AMAPT
	SCHEMBL16599463	0.81	PTGS2 (0.51)	PTGS2KDM4ELMNAKMT2AMAPT
	SCHEMBL16599337	0.80	MAPT (0.47)	PTGS2LMNAMAPTALDH1A1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.