SCHEMBL16610060

SCHEMBL16610060

C=C/C=C\C=C(/COC)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.33
GRIK2 Q13002 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL464973 0.78 ALDH1A1 (0.36) GRIK1GRIK2
SCHEMBL22842694 0.74 GRIK1 (0.35) GRIK1GRIK2
SCHEMBL17850786 0.74 TSHR (0.46) GRIK1GRIK2
SCHEMBL16527300 0.73 GRIK1 (0.43) GRIK1GRIK2
SCHEMBL16956789 0.72
SCHEMBL5609303 0.72 APEX1 (0.38) GRIK1
SCHEMBL21540332 0.71
SCHEMBL27916240 0.70
SCHEMBL19991451 0.70
SCHEMBL1160283 0.69 CAMK2A (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015044177-A1 COMPOUNDS USEFUL IN THE TREATMENT OF NEOPLASTIC DISEASES UNIVERSITÄT ZU KÖLN (DE) 2015-04-02 WO disclosed