SCHEMBL16610066

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10064159	0.85	CYP1A2 (0.49)	TYMSCA2CYP1A2CYP2C19HTT
	SCHEMBL711797	0.85	CA2 (0.58)	TYMSCA2CYP1A2CYP2C19HTT
	SCHEMBL16610056	0.84	NSD2 (0.50)	TYMS
	SCHEMBL18020594	0.84	POLB (0.45)	TYMSCYP1A2CYP2C19F2KMT2A
	SCHEMBL5171829	0.83	TYMS (0.62)	TYMSCA2CYP1A2CYP2C19HTT
	SCHEMBL714171	0.83	CA2 (0.52)	TYMSCA2CYP1A2CYP2C19HTT
	SCHEMBL22238736	0.82	TYMS (0.51)	TYMSCA2CYP1A2CYP2C19HTT
	SCHEMBL17986290	0.81	TYMS (0.47)	TYMSCA2CYP1A2CYP2C19HTT
	SCHEMBL714494	0.80	TYMS (0.57)	TYMSCA2CYP1A2CYP2C19HTT
	SCHEMBL4325460	0.80	TYMS (0.81)	TYMSF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.