Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 3/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | EDNRA | P25101 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TYMS | P04818 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL714171 | 0.86 | CA2 (0.52) | CA2CYP1A2CYP2C19HTTHIF1A | |
| SCHEMBL16610066 | 0.85 | TYMS (0.53) | CA2CYP1A2CYP2C19HTTHIF1A | |
| SCHEMBL714494 | 0.83 | TYMS (0.57) | CA2CYP1A2CYP2C19HTTHIF1A | |
| SCHEMBL12603022 | 0.81 | CA2 (0.65) | CA2CYP1A2CYP2C19HTTHIF1A | |
| SCHEMBL10064159 | 0.81 | CYP1A2 (0.49) | CA2CYP1A2CYP2C19HTTHIF1A | |
| SCHEMBL8366343 | 0.80 | CA2 (0.49) | CA2CYP1A2CYP2C19HTTHIF1A | |
| SCHEMBL12119426 | 0.80 | CA2 (0.63) | CA2CYP1A2CYP2C19HTTHIF1A | |
| SCHEMBL9674671 | 0.80 | CA2 (0.63) | CA2CYP1A2CYP2C19HTTHIF1A | |
| SCHEMBL8617605 | 0.79 | CA2 (0.55) | CA2CYP1A2CYP2C19HTTHIF1A | |
| SCHEMBL5171829 | 0.79 | TYMS (0.62) | CA2CYP1A2CYP2C19HTTHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124416-B2 | Selective and sensitive detection of mercuric ion by novel dansyl-appended calix[4] arene molecules, via fluorescence quenching | INDIAN INSTITUTE OF TECHNOLOGY DELHI (IN) | 2012-02-28 | — | — | US | disclosed |
| US-8124416-B2 | Selective and sensitive detection of mercuric ion by novel dansyl-appended calix[4] arene molecules, via fluorescence quenching | INDIAN INSTITUTE OF TECHNOLOGY DELHI (IN) | 2012-02-28 | — | — | US | disclosed |
| US-8124416-B2 | Selective and sensitive detection of mercuric ion by novel dansyl-appended calix[4] arene molecules, via fluorescence quenching | INDIAN INSTITUTE OF TECHNOLOGY DELHI (IN) | 2012-02-28 | — | — | US | disclosed |
| US-20110117657-A1 | SELECTIVE AND SENSITIVE DETECTION OF MERCURIC ION BY NOVEL DANSYL-APPENDED CALIX[4]ARENE MOLECULES, VIA FLUORESCENCE QUENCHING | EMPIRE TECHNOLOGY DEVELOPMENT LLC | 2011-05-19 | — | — | US | disclosed |
| US-20110117657-A1 | SELECTIVE AND SENSITIVE DETECTION OF MERCURIC ION BY NOVEL DANSYL-APPENDED CALIX[4]ARENE MOLECULES, VIA FLUORESCENCE QUENCHING | EMPIRE TECHNOLOGY DEVELOPMENT LLC | 2011-05-19 | — | — | US | disclosed |
| US-20110117657-A1 | SELECTIVE AND SENSITIVE DETECTION OF MERCURIC ION BY NOVEL DANSYL-APPENDED CALIX[4]ARENE MOLECULES, VIA FLUORESCENCE QUENCHING | EMPIRE TECHNOLOGY DEVELOPMENT LLC | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110117657-A1 | SELECTIVE AND SENSITIVE DETECTION OF MERCURIC ION BY NOVEL DANSYL-APPENDED CALIX[4]ARENE MOLECULES, VIA FLUORESCENCE QUENCHING | CALR, CALD1, CALU | CA2 30/4885CYP1A2 1792/4885CYP2C19 2636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.