Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | KCNK2 | O95069 | 8/20 | 0.50 |
| ▸ | KCNK10 | P57789 | 7/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | MLYCD | O95822 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9863063 | 0.81 | POLB (0.54) | HDAC4HDAC6MMP13POLBHPGD | |
| SCHEMBL620074 | 0.80 | POLB (0.66) | HDAC4HDAC6MMP13POLBHPGD | |
| SCHEMBL16599470 | 0.80 | EPHX2 (0.58) | EPHX2NR1H4CHRM4TRPV1KCNK2 | |
| SCHEMBL21995806 | 0.80 | TRPV1 (0.56) | EPHX2NR1H4TRPV1KCNK2KCNK10 | |
| SCHEMBL16599531 | 0.78 | EPHX2 (0.59) | EPHX2NR1H4CHRM4TRPV1KCNK2 | |
| SCHEMBL13741558 | 0.78 | PLK1 (0.59) | EPHX2NR1H4MMP13POLBHPGD | |
| SCHEMBL13485813 | 0.78 | TRPV1 (0.58) | EPHX2NR1H4TRPV1KCNK2KCNK10 | |
| SCHEMBL6497472 | 0.76 | TRPV1 (0.56) | EPHX2NR1H4TRPV1KCNK2KCNK10 | |
| SCHEMBL6497474 | 0.76 | PLK1 (0.61) | EPHX2NR1H4TRPV1KCNK2KCNK10 | |
| SCHEMBL16610093 | 0.76 | EPHX2 (0.53) | EPHX2NR1H4CHRM4TRPV1KCNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015044397-A1 | ORGANOMETALLIC COMPOUNDS FOR USE AS ANTHELMINTICS | Universität Zürich (CH) | 2015-04-02 | — | — | WO | disclosed |