Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.61 |
| ▸ | PELI1 | Q96FA3 | 3/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28670582 | 1.00 | ALOX5 (0.61) | ALOX5PELI1TRPV1MAOBALDH1A1 | |
| SCHEMBL16610371 | 0.84 | ALDH1A1 (0.60) | ALOX5PELI1TRPV1MAOBALDH1A1 | |
| SCHEMBL16610376 | 0.77 | APP (0.56) | ALOX5PELI1TRPV1ALDH1A1KMT2A | |
| SCHEMBL16610375 | 0.77 | ALDH1A1 (0.75) | TRPV1MAOBALDH1A1KMT2ANPC1 | |
| SCHEMBL15681754 | 0.77 | NPC1 (0.61) | ALOX5TRPV1MAOBALDH1A1KMT2A | |
| SCHEMBL27183464 | 0.76 | ALOX5 (1.00) | ALOX5PELI1TRPV1MAOBALDH1A1 | |
| SCHEMBL12334103 | 0.75 | MAOB (0.81) | ALOX5PELI1TRPV1MAOBALDH1A1 | |
| SCHEMBL2484141 | 0.75 | MAOB (0.81) | ALOX5PELI1TRPV1MAOBALDH1A1 | |
| SCHEMBL1560606 | 0.73 | MAOB (0.78) | ALOX5PELI1TRPV1MAOBALDH1A1 | |
| SCHEMBL16382869 | 0.73 | MAOB (0.78) | ALOX5PELI1TRPV1MAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107011313-B | Application of substituted cinnamide derivative in preparation of anxiolytic drugs | 天士力医药集团股份有限公司 | 2021-11-30 | — | — | CN | disclosed |
| EP-3409664-B1 | APPLICATION OF SUBSTITUTED CINNAMAMIDE DERIVATIVES IN PREPARATION OF ANTI-ANXIETY MEDICATIONS | TASLY PHARMACEUTICAL GROUP CO (CN) | 2021-01-06 | — | — | EP | disclosed |
| US-10874636-B2 | Application of substituted cinnamamide derivatives in preparation of anti-anxiety medication | TASLY PHARMACEUTICAL GROUP CO., LTD. (CN) | 2020-12-29 | — | — | US | disclosed |
| US-20190046500-A1 | APPLICATION OF SUBSTITUTED CINNAMAMIDE DERIVATIVES IN PREPARATION OF ANTI-ANXIETY MEDICATION | TASLY PHARMACEUTICAL GROUP CO., LTD. (CN) | 2019-02-14 | — | — | US | disclosed |
| WO-2015043522-A1 | TRIFLUOROMETHYL-CONTAINING AMIDE ALKALOID, MANUFACTURING METHOD AND PHARMACEUTICAL USE THEREOF | 天士力制药集团股份有限公司 | 2015-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10874636-B2 | Application of substituted cinnamamide derivatives in preparation of anti-anxiety medication | CBR3, CYP4F3, CYP4F2 | ALOX5 799/4885PELI1 4374/4885TRPV1 1447/4885 |
| US-20190046500-A1 | APPLICATION OF SUBSTITUTED CINNAMAMIDE DERIVATIVES IN PREPARATION OF ANTI-ANXIETY MEDICATION | CBR3, CYP4F3, CYP4F2 | ALOX5 799/4885PELI1 4374/4885TRPV1 1447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.