Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12863013 | 0.80 | PTGS2 (0.42) | PTGS2GAAUSP2AKR1B1CA2 | |
| SCHEMBL1292089 | 0.80 | POLB (0.56) | PTGS2GAAUSP2AKR1B1CA2 | |
| SCHEMBL1291733 | 0.80 | PTGS2 (0.42) | PTGS2GAAUSP2AKR1B1CA2 | |
| SCHEMBL10845334 | 0.80 | CYP4F2 (0.42) | PTGS2GAAUSP2POLBSMN1; SMN2 | |
| SCHEMBL12863027 | 0.79 | HSD17B10 (0.40) | PTGS2GAAUSP2AKR1B1CA2 | |
| SCHEMBL12863101 | 0.76 | CREBBP (0.43) | PTGS2GAAUSP2CA2POLB | |
| SCHEMBL12863017 | 0.76 | PTGS2 (0.39) | PTGS2GAAUSP2AKR1B1CA2 | |
| SCHEMBL12863007 | 0.76 | GAA (0.45) | PTGS2GAAUSP2CA2POLB | |
| SCHEMBL13817385 | 0.76 | USP2 (0.42) | PTGS2GAAUSP2CA2SMN1; SMN2 | |
| SCHEMBL16104885 | 0.75 | PTGS2 (0.38) | PTGS2GAAUSP2AKR1B1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2624811-B1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | FIRMENICH & CIE (CH) | 2017-06-21 | — | — | EP | disclosed |
| EP-2624811-B1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | FIRMENICH & CIE (CH) | 2017-06-21 | — | — | EP | disclosed |
| US-9382500-B2 | Benzodioxole derivatives as watery odorants | FIRMENICH SA (CH) | 2016-07-05 | — | — | US | disclosed |
| US-9382500-B2 | Benzodioxole derivatives as watery odorants | FIRMENICH SA (CH) | 2016-07-05 | — | — | US | disclosed |
| US-9382500-B2 | Benzodioxole derivatives as watery odorants | FIRMENICH SA (CH) | 2016-07-05 | — | — | US | disclosed |
| US-20150152352-A1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | FIRMENICH SA (CH) | 2015-06-04 | — | — | US | disclosed |
| US-20150152352-A1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | FIRMENICH SA (CH) | 2015-06-04 | — | — | US | disclosed |
| US-20150152352-A1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | FIRMENICH SA (CH) | 2015-06-04 | — | — | US | disclosed |
| US-8987188-B2 | Benzodioxole derivatives as watery odorants | FIRMENICH SA (CH) | 2015-03-24 | — | — | US | disclosed |
| US-8987188-B2 | Benzodioxole derivatives as watery odorants | FIRMENICH SA (CH) | 2015-03-24 | — | — | US | disclosed |
| US-8987188-B2 | Benzodioxole derivatives as watery odorants | FIRMENICH SA (CH) | 2015-03-24 | — | — | US | disclosed |
| US-20130288947-A1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | FIRMENICH SA (CH) | 2013-10-31 | — | — | US | disclosed |
| US-20130288947-A1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | FIRMENICH SA (CH) | 2013-10-31 | — | — | US | disclosed |
| US-20130288947-A1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | FIRMENICH SA (CH) | 2013-10-31 | — | — | US | disclosed |
| WO-2012045646-A1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | FIRMENICH SA (CH) | 2012-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150152352-A1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | TRPA1, BBOX1, PAOX | PTGS2 771/4885GAA 4586/4885USP2 3509/4885 |
| US-20130288947-A1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | BBOX1, CBR3, CBR1 | PTGS2 914/4885GAA 4804/4885USP2 2912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.