SCHEMBL16610679

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16611486	0.89	AKR1C3 (0.38)	PTGER1MAPK1MAPTMEN1KMT2A
	SCHEMBL16611302	0.88	ROCK2 (0.41)	CYP3A4MAPK1MAPTMEN1KMT2A
	SCHEMBL18052632	0.86	PTGER1 (0.33)	PTGER1
	SCHEMBL16611949	0.85	ZAP70 (0.41)	MAPK1USP2ALDH1A1CYP1A2HPGD
	SCHEMBL16726713	0.85	KHK (0.37)	CYP3A4MAPK1MAPTMEN1KMT2A
	SCHEMBL16611141	0.85	ZAP70 (0.39)	DGAT1KCNK3
	SCHEMBL16611480	0.85	SMN1; SMN2 (0.38)	CYP17A1CYP21A2CYP11B1PTGER1MAPK1
	Hydrochloric Acid SCHEMBL16611399	0.85	ZAP70 (0.41)	MAPK1USP2ALDH1A1CYP1A2HPGD
	SCHEMBL16611251	0.83	EED (0.39)	MAPTALDH1A1SMN1; SMN2EED
	SCHEMBL16623574	0.81	AKR1C3 (0.32)	PTGER1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.