SCHEMBL16611141

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16610871	0.87	RORC (0.38)	ZAP70MAPK11MAPK14KCNH2RORC
	SCHEMBL16611877	0.84	PRKAB2 (0.36)	ZAP70PRKAB2PRKAG1PRKAA2PRKAA1
	SCHEMBL16611352	0.81	QDPR (0.38)	MAPK11MAPK14KCNH2QDPRROCK2
	SCHEMBL16611046	0.77	PTGER1 (0.39)	MAPK14PRKAA1RORCROCK2ROCK1
	SCHEMBL16611251	0.77	EED (0.39)	RORCROCK1JAK1
	SCHEMBL16611853	0.76	MAPK1 (0.42)	MAPK11MAPK14RORCJAK1TNKS
	SCHEMBL16623574	0.74	AKR1C3 (0.32)	JAK1
	SCHEMBL16611332	0.74	SCN9A (0.38)	RORCROCK2ROCK1DGAT1
	SCHEMBL18052588	0.74	PTGER1 (0.35)	PARP1
	Hydrochloric Acid SCHEMBL16611399	0.74	ZAP70 (0.41)	ZAP70ROCK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.