SCHEMBL1661140

SCHEMBL1661140

Cc1ccc(OP(=O)(Oc2ccc(C)cc2Br)Oc2ccc(C)cc2Br)c(Br)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
CYP3A4 P08684 2/20 0.47
CYP1A2 P05177 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C19 P33261 1/20 0.45
L3MBTL1 Q9Y468 6/20 0.44
ALDH1A1 P00352 3/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
SMN1; SMN2 Q16637 4/20 0.43
TDP1 Q9NUW8 6/20 0.42
HPGD P15428 4/20 0.42
MAPT P10636 4/20 0.42
KDM4E B2RXH2 3/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
USP2 O75604 1/20 0.42
MAPK1 P28482 2/20 0.42
GAA P10253 1/20 0.41
ABL1 P00519 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7829021 0.86 TDP1 (0.47) TSHRCYP1A2CYP2D6CYP2C19L3MBTL1
SCHEMBL11360950 0.85 INPPL1 (0.48) TSHRCYP1A2CYP2D6CYP2C19L3MBTL1
Triclofos SCHEMBL11698852 0.80 SMN1; SMN2 (0.37) TSHRCYP1A2CYP2D6CYP2C19L3MBTL1
SCHEMBL29349879 0.79 CYP3A4 (0.50) TSHRCYP3A4CYP1A2CYP2C19L3MBTL1
SCHEMBL544629 0.79 MAPK1 (0.58) TSHRL3MBTL1ALDH1A1MEN1KMT2A
SCHEMBL29378605 0.79 MAPK1 (0.58) TSHRL3MBTL1ALDH1A1MEN1KMT2A
SCHEMBL108984 0.79 CYP3A4 (0.50) TSHRCYP3A4CYP1A2CYP2C19L3MBTL1
SCHEMBL30885777 0.79 L3MBTL1 (0.46) CYP1A2CYP2D6CYP2C19L3MBTL1ALDH1A1
SCHEMBL2400792 0.76 TDP1 (0.58) TSHRCYP3A4CYP1A2CYP2D6CYP2C19
SCHEMBL30811086 0.76 TDP1 (0.58) TSHRCYP3A4CYP1A2CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1607217-B1 Multilayered foil with at least one diffusion barrier layer and its use for vacuum insulation panels in the construction industry WIPAK WALSRODE GMBH & CO KG (DE) 2008-11-19 EP claimed
US-20050287370-A1 Film laminate with at least one diffusion-barrier layer and its use in vacuum insulation panels in the construction sector WIPAK WALSRODE GMBH CO. & KG 2005-12-29 US claimed
EP-1607217-A1 Multilayered foil with at least one diffusion barrier layer and its use for vacuum insulation panels in the construction industry Wipak Walsrode GmbH & Co. KG (DE) 2005-12-21 EP claimed
US-3936562-A Fire retardant fabrics UNITED MERCHANTS AND MANUFACTURERS, INC. (US) 1976-02-03 US claimed
JP-60215038-A None JP disclosed
US-12629918-B2 Punched article, in particular for permanently closing holes TESA SE (DE) 2026-05-19 US disclosed
EP-4377080-B1 PUNCHED ARTICLE, IN PARTICULAR FOR PERMANENTLY CLOSING HOLES TESA SE (DE) 2025-05-28 EP disclosed
US-20250083410-A1 PUNCHED ARTICLE, IN PARTICULAR FOR PERMANENTLY CLOSING HOLES TESA SE (DE) 2025-03-13 US disclosed
EP-4377080-A1 PUNCHED ARTICLE, IN PARTICULAR FOR PERMANENTLY CLOSING HOLES TESA SE (DE) 2024-06-05 EP disclosed
CN-114013386-B Stamping, in particular for permanently closing holes 德莎欧洲股份公司 2024-04-16 CN disclosed
CN-117769489-A Die-cut piece, in particular for permanently closing holes 德莎欧洲股份公司 2024-03-26 CN disclosed
US-11850835-B2 Production of composite materials made of film, solid adhesive polymer, and a polyurethane layer BASF COATINGS GMBH (DE) 2023-12-26 US disclosed
WO-1980002142-A1 PROCESS FOR THE PRODUCTION OF ALKALI METAL-CELLULOSE-SILICATES AND THEIR REACTION PRODUCTS BLOUNT D (US) 1980-10-16 WO disclosed
US-4226982-A ALKALI METAL CELLULOSE PRODUCED BY REACTION WITH ALKALI METAL HYDROXIDE BLOUNT DAVID H 1980-10-07 US disclosed
US-4220757-A Process for the production of alkali metal-cellulose-silicates and their reaction products BLOUNT DAVID H 1980-09-02 US disclosed
US-4185147-A Production of amino-silicate compounds, condensation resinous products and foam BLOUNT DAVID H 1980-01-22 US disclosed
US-4097422-A POLYISOCYANATE, SILICA SOL, CONCRETES BAYER AKTIENGESELLSCHAFT (DT) 1978-06-27 US disclosed
US-4052347-A POLYISOCYANATE, ALKALI METAL SILICATE BAYER AKTIENGESELLSCHAFT (DT) 1977-10-04 US disclosed
US-3983081-A POLYISOCYANATE, SILICATE BAYER AKTIENGESELLSCHAFT (DT) 1976-09-28 US disclosed
US-3936562-A Fire retardant fabrics UNITED MERCHANTS AND MANUFACTURERS, INC. (US) 1976-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12629918-B2 Punched article, in particular for permanently closing holes DCX, ACTN1, PTN TSHR 4824/4885CYP3A4 4684/4885CYP1A2 4275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.