Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.48 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.41 |
| ▸ | LPL | P06858 | 2/20 | 0.41 |
| ▸ | P4HB | P07237 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F11 | P03951 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2550198 | 0.80 | LIPG (0.43) | AAK1CA1CA2CA9LIPG | |
| SCHEMBL15615744 | 0.79 | LPL (0.49) | AAK1CA1CA2CA9HIF1A | |
| SCHEMBL31188697 | 0.78 | CYP1A2 (0.51) | AAK1CA1CA2CA9LIPG | |
| SCHEMBL2553821 | 0.78 | P4HB (0.42) | AAK1CA1CA2CA9LIPG | |
| SCHEMBL24467420 | 0.78 | LPL (0.54) | AAK1CA1CA2CA9HIF1A | |
| SCHEMBL28334985 | 0.78 | LPL (0.54) | AAK1CA1CA2CA9HIF1A | |
| SCHEMBL15189795 | 0.77 | AAK1 (0.43) | AAK1CA1CA2CA9HIF1A | |
| SCHEMBL20424266 | 0.77 | LPL (0.46) | AAK1CA1CA2CA9HIF1A | |
| SCHEMBL16468330 | 0.76 | HIF1A (0.48) | MTNR1AMTNR1BAAK1CA1CA2 | |
| SCHEMBL1561011 | 0.75 | HIF1A (0.47) | MTNR1AMTNR1BAAK1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857404-A1 | IMIDAZO[1,2-b]PYRIDAZINE DERIVATIVE AS KINASE INHIBITOR | Daiichi Sankyo Co., Ltd. (JP) | 2015-04-08 | — | — | EP | disclosed |