Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | STAT1 | P42224 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16803696 | 0.86 | SMN1; SMN2 (0.34) | POLBSMN1; SMN2 | |
| SCHEMBL16612730 | 0.81 | POLB (0.47) | POLBAGPAT2KMT2AMEN1L3MBTL1 | |
| SCHEMBL16613190 | 0.81 | POLB (0.48) | POLB | |
| SCHEMBL10280699 | 0.80 | POLB (0.48) | POLBAGPAT2KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL21925159 | 0.80 | POLB (0.48) | POLBKMT2AMEN1L3MBTL1CYP1A2 | |
| SCHEMBL16612304 | 0.80 | POLB (0.48) | POLBKMT2AMEN1NPSR1LMNA | |
| SCHEMBL16612482 | 0.80 | POLB (0.50) | POLBSMN1; SMN2RAB9ALMNAALDH1A1 | |
| SCHEMBL15412037 | 0.78 | POLB (0.46) | POLBAGPAT2KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL16611998 | 0.78 | POLB (0.53) | POLBKMT2AMEN1L3MBTL1CRHR1 | |
| SCHEMBL15411967 | 0.78 | POLB (0.49) | POLBKMT2AMEN1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857397-B1 | FUSED HETEROCYCLIC COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2020-04-08 | — | — | EP | disclosed |
| US-9364000-B2 | Method of controlling pests with fused heterocyclic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-06-14 | — | — | US | disclosed |
| US-9364000-B2 | Method of controlling pests with fused heterocyclic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-06-14 | — | — | US | disclosed |
| US-20150373982-A1 | METHOD OF CONTROLLING PESTS WITH FUSED HETEROCYCLIC COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2015-12-31 | — | — | US | disclosed |
| US-20150373982-A1 | METHOD OF CONTROLLING PESTS WITH FUSED HETEROCYCLIC COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2015-12-31 | — | — | US | disclosed |
| US-20150166573-A1 | FUSED HETEROCYCLIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-06-18 | — | — | US | disclosed |
| US-20150166573-A1 | FUSED HETEROCYCLIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-06-18 | — | — | US | disclosed |
| EP-2857397-A1 | FUSED HETEROCYCLIC COMPOUND | Sumitomo Chemical Company Limited (JP) | 2015-04-08 | — | — | EP | disclosed |
| EP-2857397-A1 | FUSED HETEROCYCLIC COMPOUND | Sumitomo Chemical Company Limited (JP) | 2015-04-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150373982-A1 | METHOD OF CONTROLLING PESTS WITH FUSED HETEROCYCLIC COMPOUND | NR4A1, NR2E1, NR0B1 | POLB 4183/4885AGPAT2 2561/4885KMT2A 1682/4885 |
| US-20150166573-A1 | FUSED HETEROCYCLIC COMPOUND | NR4A1, NR2E1, NR0B2 | POLB 3690/4885AGPAT2 2787/4885KMT2A 1379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.