⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16612447 | 0.80 | KMT2A (0.44) | — | |
| SCHEMBL16612732 | 0.80 | KMT2A (0.44) | — | |
| SCHEMBL5944497 | 0.77 | POLB (0.42) | — | |
| SCHEMBL56361 | 0.71 | MAPT (0.40) | — | |
| SCHEMBL16612898 | 0.71 | ALDH1A1 (0.44) | — | |
| SCHEMBL5944513 | 0.70 | APOBEC3A (0.40) | — | |
| SCHEMBL9417714 | 0.69 | LMNA (0.38) | — | |
| SCHEMBL28660752 | 0.68 | MAPT (0.38) | — | |
| SCHEMBL7596929 | 0.68 | MAPT (0.38) | — | |
| SCHEMBL5281905 | 0.68 | APOBEC3A (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857446-B1 | TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE | SUMITOMO RUBBER IND (JP) | 2018-03-07 | — | — | EP | disclosed |
| US-9790359-B2 | Tread rubber composition and pneumatic tire | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2017-10-17 | — | — | US | disclosed |
| US-20150099823-A1 | TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2015-04-09 | — | — | US | disclosed |
| EP-2857446-A1 | TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE | Sumitomo Rubber Industries, Ltd. (JP) | 2015-04-08 | — | — | EP | disclosed |