Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12479162 | 0.85 | HCRTR2 (0.39) | HCRTR2POLB | |
| SCHEMBL16612872 | 0.85 | HCRTR2 (0.41) | HCRTR2 | |
| SCHEMBL16612772 | 0.83 | KMT2A (0.46) | HCRTR2 | |
| SCHEMBL16612825 | 0.79 | HCRTR2 (0.41) | HCRTR2 | |
| SCHEMBL16612738 | 0.79 | HCRTR2 (0.36) | HCRTR2 | |
| SCHEMBL16612742 | 0.79 | HCRTR2 (0.39) | HCRTR2POLB | |
| SCHEMBL16612726 | 0.77 | ALDH1A1 (0.40) | HCRTR2 | |
| SCHEMBL16612778 | 0.75 | HCRTR2 (0.40) | HCRTR2POLB | |
| SCHEMBL16612690 | 0.74 | HCRTR2 (0.35) | HCRTR2 | |
| SCHEMBL16612600 | 0.73 | HCRTR2 (0.43) | HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675801-B1 | NOVEL PYRAZOLE AND IMIDAZOLE DERIVATIVES USEFUL AS OREXIN ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2015-04-08 | — | — | EP | claimed |