Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.32 |
| ▸ | CDK2 | P24941 | 4/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 4/20 | 0.32 |
| ▸ | AURKA | O14965 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16612738 | 0.88 | HCRTR2 (0.36) | HCRTR2IRAK4SYKCCNA2CDK2 | |
| SCHEMBL16612726 | 0.86 | ALDH1A1 (0.40) | HCRTR2IRAK4 | |
| SCHEMBL16612683 | 0.79 | FDPS (0.45) | HCRTR2SYKCCNA2CDK2CCNA1 | |
| SCHEMBL16612872 | 0.78 | HCRTR2 (0.41) | HCRTR2SYKCCNA2CDK2CCNA1 | |
| SCHEMBL16612772 | 0.78 | KMT2A (0.46) | HCRTR2SYK | |
| SCHEMBL16612841 | 0.75 | MAPT (0.40) | HCRTR2 | |
| SCHEMBL16612752 | 0.75 | HCRTR2 (0.38) | HCRTR2 | |
| SCHEMBL16612865 | 0.74 | HCRTR2 (0.38) | HCRTR2 | |
| SCHEMBL16612825 | 0.74 | HCRTR2 (0.41) | HCRTR2 | |
| SCHEMBL16612665 | 0.71 | HCRTR2 (0.39) | HCRTR2IRAK4SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675801-B1 | NOVEL PYRAZOLE AND IMIDAZOLE DERIVATIVES USEFUL AS OREXIN ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2015-04-08 | — | — | EP | disclosed |