Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 13/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4667450 | 0.89 | HSD17B2 (0.38) | HSD17B2KDM4EHPGDHSD17B10HSD17B1 | |
| SCHEMBL3089511 | 0.86 | HSD17B2 (0.37) | HSD17B2KDM4EHPGDHSD17B10HSD17B1 | |
| SCHEMBL3088157 | 0.85 | HSD17B2 (0.48) | HSD17B2HSD17B1 | |
| SCHEMBL16612801 | 0.82 | HSD17B2 (0.38) | HSD17B2KDM4EHPGDHSD17B10HSD17B1 | |
| SCHEMBL4901202 | 0.77 | KDM4E (0.54) | HSD17B2KDM4EHSD17B1MAPTGAA | |
| SCHEMBL3079789 | 0.75 | TYMS (0.39) | KDM4EHPGDHSD17B10MAPTALDH1A1 | |
| SCHEMBL3092091 | 0.72 | HSD17B2 (0.40) | HSD17B2KDM4EHPGDHSD17B10HSD17B1 | |
| SCHEMBL3082984 | 0.72 | HSD17B2 (0.32) | HSD17B2 | |
| SCHEMBL3083394 | 0.70 | ELANE (0.30) | — | |
| SCHEMBL16372098 | 0.69 | CUL4A (0.39) | HSD17B2KDM4EHPGDHSD17B10HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2144879-B1 | PYRIDON CARBOXAMIDES, AGENTS CONTAINING THESE BUT NOT IMPACTING USEFUL PLANTS AND METHOD FOR THEIR MANUFACTURE AND APPLICATION | BAYER IP GMBH (DE) | 2015-04-08 | — | — | EP | disclosed |