Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 13/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.32 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16612938 | 0.89 | HSD17B2 (0.37) | HSD17B2KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL3088157 | 0.88 | HSD17B2 (0.48) | HSD17B2HSD17B1 | |
| SCHEMBL16612801 | 0.84 | HSD17B2 (0.38) | HSD17B2KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL3082984 | 0.83 | HSD17B2 (0.32) | HSD17B2 | |
| SCHEMBL3089511 | 0.83 | HSD17B2 (0.37) | HSD17B2KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL4904432 | 0.76 | KDM4E (0.57) | HSD17B2KDM4EMAPTGAAHSD17B1 | |
| SCHEMBL16372098 | 0.74 | CUL4A (0.39) | HSD17B2KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL3092091 | 0.74 | HSD17B2 (0.40) | HSD17B2KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL3089100 | 0.73 | CUL4A (0.38) | HSD17B2KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL3079789 | 0.71 | TYMS (0.39) | KDM4EHPGDHSD17B10MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019012-A1 | USE OF SELECTED PYRIDONE CARBOXAMIDES OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | Bayer CropScience AG (DE) | 2016-05-18 | — | — | EP | disclosed |
| EP-2144879-B1 | PYRIDON CARBOXAMIDES, AGENTS CONTAINING THESE BUT NOT IMPACTING USEFUL PLANTS AND METHOD FOR THEIR MANUFACTURE AND APPLICATION | BAYER IP GMBH (DE) | 2015-04-08 | — | — | EP | disclosed |
| WO-2015004040-A1 | USE OF SELECTED PYRIDONE CARBOXAMIDES OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2015-01-15 | — | — | WO | disclosed |
| EP-1987717-A1 | Pyridon carboxamides, agents containing these but not impacting useful plants and method for their manufacture and application | Bayer CropScience AG (DE) | 2008-11-05 | — | — | EP | disclosed |