Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 2/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CUL4A | Q13619 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3071416 | 0.83 | HSD17B2 (0.34) | HSD17B2HSD17B1 | |
| SCHEMBL3088157 | 0.76 | HSD17B2 (0.48) | HSD17B2HSD17B1 | |
| SCHEMBL16612801 | 0.76 | HSD17B2 (0.38) | HSD17B2HSD17B1KDM4EHSD17B10HPGD | |
| SCHEMBL4898553 | 0.75 | KDM4E (0.60) | HSD17B2HSD17B1KDM4EHSD17B10HPGD | |
| SCHEMBL4667450 | 0.74 | HSD17B2 (0.38) | HSD17B2HSD17B1KDM4EHSD17B10HPGD | |
| SCHEMBL17844559 | 0.72 | KDM4E (0.51) | KDM4EHSD17B10HPGDGAAMAPT | |
| SCHEMBL9571014 | 0.72 | PARP1 (0.38) | KDM4EHSD17B10HPGDGAAMAPT | |
| SCHEMBL3089511 | 0.72 | HSD17B2 (0.37) | HSD17B2HSD17B1KDM4EHSD17B10HPGD | |
| SCHEMBL16612938 | 0.72 | HSD17B2 (0.37) | HSD17B2HSD17B1KDM4EHSD17B10HPGD | |
| SCHEMBL16612698 | 0.71 | CUL4A (0.40) | KDM4EHSD17B10HPGDGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2144879-B1 | PYRIDON CARBOXAMIDES, AGENTS CONTAINING THESE BUT NOT IMPACTING USEFUL PLANTS AND METHOD FOR THEIR MANUFACTURE AND APPLICATION | BAYER IP GMBH (DE) | 2015-04-08 | — | — | EP | disclosed |
| EP-2144879-A2 | PYRIDONECARBOXAMIDES CROP PROTECTION AGENTS CONTAINING THE SAME METHOD FOR PRODUCTION AND USE THEREOF | Bayer CropScience AG (DE) | 2010-01-20 | — | — | EP | disclosed |
| WO-2008131860-A2 | PYRIDONECARBOXAMIDES CROP PROTECTION AGENTS CONTAINING THE SAME METHOD FOR PRODUCTION AND USE THEREOF | BAYER CROPSCIENCE AG (DE) | 2008-11-06 | — | — | WO | disclosed |
| EP-1987717-A1 | Pyridon carboxamides, agents containing these but not impacting useful plants and method for their manufacture and application | Bayer CropScience AG (DE) | 2008-11-05 | — | — | EP | disclosed |