SCHEMBL3082984

SCHEMBL3082984

O=C(O)Oc1ccc(C(F)(F)Cl)[nH]c1=O

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HSD17B2 P37059 10/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3077346 0.87 HSD17B2 (0.40) HSD17B2
SCHEMBL4667450 0.83 HSD17B2 (0.38) HSD17B2
SCHEMBL3083394 0.81 ELANE (0.30)
SCHEMBL16371315 0.72 DAO (0.30)
SCHEMBL16612938 0.72 HSD17B2 (0.37) HSD17B2
SCHEMBL3071416 0.70 HSD17B2 (0.34) HSD17B2
SCHEMBL3081670 0.70 HSD17B2 (0.42) HSD17B2
SCHEMBL4904432 0.70 KDM4E (0.57) HSD17B2
SCHEMBL3088157 0.70 HSD17B2 (0.48) HSD17B2
SCHEMBL16612801 0.67 HSD17B2 (0.38) HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2144879-B1 PYRIDON CARBOXAMIDES, AGENTS CONTAINING THESE BUT NOT IMPACTING USEFUL PLANTS AND METHOD FOR THEIR MANUFACTURE AND APPLICATION BAYER IP GMBH (DE) 2015-04-08 EP disclosed
EP-2144879-A2 PYRIDONECARBOXAMIDES CROP PROTECTION AGENTS CONTAINING THE SAME METHOD FOR PRODUCTION AND USE THEREOF Bayer CropScience AG (DE) 2010-01-20 EP disclosed
WO-2008131860-A2 PYRIDONECARBOXAMIDES CROP PROTECTION AGENTS CONTAINING THE SAME METHOD FOR PRODUCTION AND USE THEREOF BAYER CROPSCIENCE AG (DE) 2008-11-06 WO disclosed
EP-1987717-A1 Pyridon carboxamides, agents containing these but not impacting useful plants and method for their manufacture and application Bayer CropScience AG (DE) 2008-11-05 EP disclosed