Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 9/20 | 0.52 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.52 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.52 |
| ▸ | GGH | Q92820 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28663570 | 1.00 | FOLH1 (0.52) | FOLH1NAALAD2RIMKLAGGHCYP2D6 | |
| Hydrochloric Acid SCHEMBL29419567 | 0.98 | FOLH1 (0.50) | FOLH1NAALAD2RIMKLAGGHCYP2D6 | |
| SCHEMBL31229070 | 0.81 | FOLH1 (0.48) | FOLH1NAALAD2RIMKLAGGHCYP2D6 | |
| SCHEMBL20528927 | 0.81 | KDM4E (0.38) | FOLH1NAALAD2RIMKLAGGHCYP2D6 | |
| SCHEMBL15285862 | 0.81 | KDM4E (0.38) | FOLH1NAALAD2RIMKLAGGHCYP2D6 | |
| SCHEMBL31229499 | 0.79 | CYP2D6 (0.47) | FOLH1NAALAD2RIMKLAGGHCYP2D6 | |
| SCHEMBL31229164 | 0.79 | FOLH1 (0.46) | FOLH1NAALAD2RIMKLAGGHCYP2D6 | |
| SCHEMBL31229147 | 0.78 | FOLH1 (0.48) | FOLH1NAALAD2RIMKLAGGHCYP2D6 | |
| SCHEMBL21774466 | 0.78 | LMNA (0.44) | FOLH1LMNA | |
| SCHEMBL28340760 | 0.78 | LMNA (0.44) | FOLH1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113509550-B | Molecular brush nano particle and preparation method and application thereof | 广州市第一人民医院（广州消化疾病中心、广州医科大学附属市一人民医院、华南理工大学附属第二医院） | 2023-04-14 | — | — | CN | claimed |
| CN-113512200-B | Molecular brush polymer with poly-L-glutamic acid ester as main chain, and preparation method and application thereof | 广州市第一人民医院（广州消化疾病中心、广州医科大学附属市一人民医院、华南理工大学附属第二医院） | 2022-07-08 | — | — | CN | claimed |
| CN-113512200-A | Molecular brush polymer with poly-L-glutamic acid ester as main chain, and preparation method and application thereof | 广州市第一人民医院（广州消化疾病中心、广州医科大学附属市一人民医院、华南理工大学附属第二医院） | 2021-10-19 | — | — | CN | claimed |
| CN-113509550-A | Molecular brush nano particle and preparation method and application thereof | 广州市第一人民医院（广州消化疾病中心、广州医科大学附属市一人民医院、华南理工大学附属第二医院） | 2021-10-19 | — | — | CN | claimed |
| CN-114127974-B | Markers for labeling biomolecules | 上海宸安生物科技有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-113509550-B | Molecular brush nano particle and preparation method and application thereof | 广州市第一人民医院（广州消化疾病中心、广州医科大学附属市一人民医院、华南理工大学附属第二医院） | 2023-04-14 | — | — | CN | disclosed |
| CN-113512200-B | Molecular brush polymer with poly-L-glutamic acid ester as main chain, and preparation method and application thereof | 广州市第一人民医院（广州消化疾病中心、广州医科大学附属市一人民医院、华南理工大学附属第二医院） | 2022-07-08 | — | — | CN | disclosed |
| CN-114127974-A | Markers for labeling biomolecules | 上海宸安生物科技有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-113509550-A | Molecular brush nano particle and preparation method and application thereof | 广州市第一人民医院（广州消化疾病中心、广州医科大学附属市一人民医院、华南理工大学附属第二医院） | 2021-10-19 | — | — | CN | disclosed |
| CN-113512200-A | Molecular brush polymer with poly-L-glutamic acid ester as main chain, and preparation method and application thereof | 广州市第一人民医院（广州消化疾病中心、广州医科大学附属市一人民医院、华南理工大学附属第二医院） | 2021-10-19 | — | — | CN | disclosed |
| EP-2646048-A2 | STABLE HELICAL IONIC POLYPEPTIDES | The Board of Trustees of the University of Illinois (US) | 2013-10-09 | — | — | EP | disclosed |
| EP-2493868-A2 | POLY(PROPARGYL-L-GLUTAMATE) AND DERIVATIVES THEREOF | Massachusetts Institute Of Technology (US) | 2012-09-05 | — | — | EP | disclosed |
| US-8222359-B2 | Poly(propargyl-L-glutamate) and derivatives thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-07-17 | — | — | US | disclosed |
| WO-2012075147-A2 | STABLE HELICAL IONIC POLYPEPTIDES | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-06-07 | — | — | WO | disclosed |
| WO-2011056645-A2 | POLY(PROPARGYL-L-GLUTAMATE) AND DERIVATIVES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-05-12 | — | — | WO | disclosed |
| US-20110097419-A1 | Poly(Propargyl-L-Glutamate) and Derivatives Thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110097419-A1 | Poly(Propargyl-L-Glutamate) and Derivatives Thereof | GLUL, QPCTL, QPCT | FOLH1 111/4885NAALAD2 50/4885RIMKLA 52/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.