Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4191882 | 0.81 | MAPT (0.53) | PDE4DMAPTHSD17B10LMNACREBBP | |
| SCHEMBL4024140 | 0.79 | HDAC1 (0.57) | PDE4DMAPTHSD17B10LMNASMN1; SMN2 | |
| SCHEMBL27796809 | 0.79 | MEN1 (0.69) | MAPTLMNASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL8387145 | 0.77 | CNR2 (0.66) | MAPTLMNASMPD1HDAC1HDAC2 | |
| SCHEMBL566516 | 0.74 | POLB (0.66) | MAPTHSD17B10LMNACREBBPALDH1A1 | |
| SCHEMBL9662476 | 0.74 | SMN1; SMN2 (0.59) | PDE4DMAPTHSD17B10SMN1; SMN2CREBBP | |
| SCHEMBL8420347 | 0.73 | MAPT (0.59) | PDE4DMAPTHSD17B10LMNASMN1; SMN2 | |
| SCHEMBL4020644 | 0.73 | HDAC1 (0.58) | PDE4DMAPTLMNASMN1; SMN2SMPD1 | |
| SCHEMBL11250057 | 0.73 | SMPD1 (0.65) | MAPTLMNASMPD1ALDH1A1KDM4E | |
| SCHEMBL27711055 | 0.72 | MAPK1 (0.64) | PDE4DMAPTHSD17B10SMN1; SMN2SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874722-B1 | HYDROXAMIC ACID DERIVATIVES AND THE PREPARATION METHOD THEREOF | AMOREPACIFIC CORP (KR) | 2015-04-08 | — | — | EP | disclosed |