Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | CASP6 | P55212 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | TPMT | P51580 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177336 | 0.92 | TSHR (0.77) | POLBCASP6TSHRKMT2AHPGD | |
| SCHEMBL7334285 | 0.92 | CA12 (0.69) | POLBCASP6TSHRHPGDCA12 | |
| SCHEMBL7336764 | 0.91 | ALDH1A1 (0.67) | POLBCASP6TSHRHPGDALDH1A1 | |
| SCHEMBL4023882 | 0.91 | POLB (0.64) | POLBCASP6TSHRHPGDALDH1A1 | |
| SCHEMBL1199892 | 0.90 | ALDH1A1 (0.69) | POLBCASP6TSHRHPGDALDH1A1 | |
| SCHEMBL1199847 | 0.90 | ALDH1A1 (0.69) | POLBCASP6TSHRHPGDALDH1A1 | |
| SCHEMBL1200986 | 0.90 | ALDH1A1 (0.69) | POLBCASP6TSHRHPGDALDH1A1 | |
| SCHEMBL1201602 | 0.90 | ALDH1A1 (0.69) | POLBCASP6TSHRHPGDALDH1A1 | |
| SCHEMBL9512861 | 0.90 | ALDH1A1 (0.65) | POLBCASP6TSHRHPGDALDH1A1 | |
| SCHEMBL1231278 | 0.90 | ALDH1A1 (0.69) | POLBCASP6TSHRHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4069252-A1 | PDIA4 INHIBITORS AND USE THEREOF FOR INHIBITING SS-CELL PATHOGENESIS AND TREATING DIABETES | Academia Sinica (CN) | 2022-10-12 | — | — | EP | disclosed |
| US-9181182-B2 | S1P receptors modulators | AKAAL PHARMA PTY LTD (AU) | 2015-11-10 | — | — | US | disclosed |
| EP-1874722-B1 | HYDROXAMIC ACID DERIVATIVES AND THE PREPARATION METHOD THEREOF | AMOREPACIFIC CORP (KR) | 2015-04-08 | — | — | EP | disclosed |
| US-20120034270-A1 | S1P Receptors Modulators | AKAAL PHARMA PTY LTD (AU) | 2012-02-09 | — | — | US | disclosed |
| EP-2344446-A1 | S1P RECEPTORS MODULATORS | Akaal Pharma Pty Ltd (AU) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010042998-A1 | S1P RECEPTORS MODULATORS | AKAAL PHARMA PTY LTD (AU) | 2010-04-22 | — | — | WO | disclosed |
| US-7485750-B2 | Hydroxamic acid derivatives and the preparation method thereof | AMOREPACIFIC CORPORATION (KR) | 2009-02-03 | — | — | US | disclosed |
| US-20080242730-A1 | Hydroxamic Acid Derivatives and the Preparation Method Thereof | AMOREPACIFIC CORPORATION (KR) | 2008-10-02 | — | — | US | disclosed |
| EP-1874722-A1 | HYDROXAMIC ACID DERIVATIVES AND THE PREPARATION METHOD THEREOF | Amorepacific Corporation (KR) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006118380-A1 | HYDROXAMIC ACID DERIVATIVES AND THE PREPARATION METHOD THEREOF | AMOREPACIFIC CORPORATION (KR) | 2006-11-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120034270-A1 | S1P Receptors Modulators | S1PR1, S1PR5, S1PR3 | POLB 4275/4885CASP6 1952/4885TSHR 667/4885 |
| US-20080242730-A1 | Hydroxamic Acid Derivatives and the Preparation Method Thereof | COL14A1, CUTA, COL2A1 | POLB 1096/4885CASP6 681/4885TSHR 4670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.